The effect of eight weeks of CX WORX training on serum levels of Afamin and insulin resistance in overweight women

  Afamin is a new biomarker of increased the risk of metabolic disease and is associated with insulin resistance. The aim of this study was to investigate the effect of eight weeks of CX WORX training on serum levels of Afamin and insulin resistance in overweight women.

 In this quasi-experimental study, 24 available women (body mass index above 25) were purposefully selected and randomly divided into two groups of control (age: 29.55±4.7 year, height: 162.5± 3.87 cm, weight: 72.25±6.73 kg) and exercise (age: 28.65±3.95 year, height: 164.5± 4.66 cm, weight: 75.83±5.71 kg). The CX WORX training program was performed includes initial warm-up, abdominal strength (1), static strength (1), static strength (2), abdominal strength (2), abdominal strength (3), and exercise (crunch, plank and weight plate), 3 sessions per week for eight weeks. Serum Afamin concentration was measured using ELISA method, and insulin resistance was calculated using the HOMA-IR model formula and fasting glucose and insulin values. Data were analyzed using independent and pair÷ed t-test.

The results showed that after the intervention, BMI (p=0.02), WHR (p=0.004), insulin resistance (p=0.0001) and Afamin (p=0.0001) in the exercise group were significantly lower compared to the control group. Also, after the intervention, BMI (p=0.001), WHR (p=0.02), insulin resistance (p=0.003) and Afamin (p=0.003) in overweight women in the exercise group decreased compared to the pre-test (P<0.001).

According to the results, it seems that CX WORX training can help to reduce afamine levels and improving insulin resistance in overweight people.