A review of the effect of exercise training and antioxidant supplements in patients with asthma

 Asthma is a chronic inflammatory disease characterized by respiratory symptoms, variable airway obstruction, airway hyperresponsiveness, and airway inflammation. In the present study, a review of the effect of exercise and antioxidant supplements in patients with asthma has been discussed.

 Using several databases including Google Scholar, Web of Science, Science Direct, PubMed, and Scopus, and using the titles of asthma and the names of their types and related names for the keywords of asthma until 2022, a search was made. At first, by limiting the search, irrelevant and repeated studies were removed, and after reviewing the titles, abstracts, and full texts, suitable studies were included in the current research.

 Focusing on studies that focused on the effects of exercise and antioxidant supplements in patients with asthma, it can be said that exercise in these patients through pathophysiological mechanisms has been able to play a role in reducing the harmful effects of asthma. So that regular aerobic and breathing exercises are recommended to improve this disease. Also, the lung tissue of asthmatic patients is exposed to oxidative stress due to the production of reactive oxygen and nitrogen species. For this reason, taking into account the reduction of antioxidant enzymes, we will see an increase in apoptosis, the loss of airway epithelial cells, and a decrease in airway regeneration. Therefore, studies have pointed to the positive role of antioxidants in patients with asthma.