Optimization of reaction parameters for 5,5’-methylenebis (salicylaldehyde) synthesis using sonochemical approach

Article Type:
Research/Original Article (دارای رتبه معتبر)
Maximizing the yield of synthesizing compounds is as a serious production concern. Therefore, developing a new and more effective synthesis method is necessary for practicable research. In this study, a novel approach was described to the synthesis of 5,5’-methylenebis (salicylaldehyde) (MBS) using a sonochemical technique. Response surface methodology (RSM) under Design of experiments (DOE) using central composite design (CCD) was developed to acquire a high yield through optimizing three practicable parameters. The quadratic model resulting from processing analysis of variance (ANOVA) showed a good agreement between the experimental and predicted responses, as (R2 values of 0.9970 with adjusted and predicted R2 values of 0.9944 and 0.9806, respectively) implying good conformity between predicted and experimental values. The highest yield (19.3%) approach was obtained after 8 hours at 80 °C with a S:F ratio = 1.4%. Furthermore, the characterization, such as FTIR, 1H-NMR, 13CNMR, and EI-Mass spectrometry results support the MBS structure achieved through the sonochemical method.
Eurasian Chemical Communications, Volume:5 Issue: 4, Apr 2023
335 to 342
دانلود و مطالعه متن این مقاله با یکی از روشهای زیر امکان پذیر است:
اشتراک شخصی
با عضویت و پرداخت آنلاین حق اشتراک یک‌ساله به مبلغ 1,390,000ريال می‌توانید 70 عنوان مطلب دانلود کنید!
اشتراک سازمانی
به کتابخانه دانشگاه یا محل کار خود پیشنهاد کنید تا اشتراک سازمانی این پایگاه را برای دسترسی نامحدود همه کاربران به متن مطالب تهیه نمایند!
  • حق عضویت دریافتی صرف حمایت از نشریات عضو و نگهداری، تکمیل و توسعه مگیران می‌شود.
  • پرداخت حق اشتراک و دانلود مقالات اجازه بازنشر آن در سایر رسانه‌های چاپی و دیجیتال را به کاربر نمی‌دهد.
In order to view content subscription is required

Personal subscription
Subscribe magiran.com for 70 € euros via PayPal and download 70 articles during a year.
Organization subscription
Please contact us to subscribe your university or library for unlimited access!