Effect of growth hormone on histomorphometerical parameters of testis aftermethotrexate administration in rat
Safavi , S.E. , Khayat Nouri , M.H
Methotrexate (MTX) is a chemotherapeutic agent that used for the treatment of a variety of tumors and inflammatory diseases. The aim of this study was investigated the effect of growth hormone on histomorphometerical parameters of testis after methotrexate administration in rat. In this experimental study, the eighty male wistarrat were selected and randomly divided into eight groups; control (n=20) and test (n=60). One and two test groups were received 0.3mg/kg GH (IP) for 14 and 28 consequence days, respectively. Three and four test groups were received 1mg/kg MTX (IP) per week for 14 and 28 consequence days, respectively. Five and six test groups were received 1mg/kg MTX (IP) with 0.3mg/kg GH (IP) (MTX+GH) for 14 and 28consequence days, respectively
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