Investigating Effect of Drug Use on Short-term Complications and Bleeding in Patients Undergoing Off-pump CABG (OPCAB)

Opioid abuse is a major social and health problem in many parts of the world especially in Iran. There are not much information about effect of drugs (addiction) on short-term complications and bleeding after CABG. This study aimed to assess the relationship between addiction with short-term complications and bleeding after CABG. This is a descriptive study in which 100 male patients who underwent off-pump CABG in Afshar hospital in yazd were followed during 3 months to investigate their short-term complications. preoperative and post-operative Hb، Plt، Pt، Ptt، bleeding and packed cells after operation were recorded. Then، collected data was analyzed by chi-square، fisher and exact test. In this study، 30 patients were addicts and 70 male patients were non-addicts. All patients were males and similar in preoperative characteristics such as HTN، DM، HLP، CAD، LIMA usage and NYHA FC. Addicted patients were younger than non-addicts and most of them were cigarette smokers. Regarding medical and dietary recommendation after operation، addicted patients observed these recommendation significantly less than non-addicted patients. After operation، pulmonary، neurologic and infective complications were significantly more common in addicted patients. According the study results and other similar studies، drug use in patients with cardiovascular disease is noticeable. Moreover، regarding the postoperative outcomes in addicted patients، more studies needs to be conducted in this field.