Effect of Coenzyme Q10 Supplementation on Exercise Response in Some Hematological Parameters in Non-Athletes Men

There is limited available data about the effects of antioxidant supplements on changes of hematological parameters after exercise. This study was carried out to investigate the effect of short-term CoenzymeQ10 supplementation on white blood cells, hemoglobin and red blood cell indices in non-athlete men after relatively intense running. Twenty healthy inactive men (25±3 years, fat 13±2. % and VO2max 41±2 ml/kg/min) in a randomized and double-blind design were allocated in two equal groups: supplement (2.5 mg/kg/day Coenzyme Q10) and placebo (2.5 mg/kg/day dextrose) groups. After the 14-day supplementation therapy, all subjects were participated in an aerobic exercise with 75% VO2max on the treadmill for 30 minutes. Blood samples obtained before the Q10 supplementation along with before and after the exercise protocol. Ingestion 14-day coenzymQ10 supplementation on indexs (RBC, Hg, MCV, MCH, MCHC, Hct, WBC,PLT, lanphosit percentages, notrophils and other blood cells) had no significant effect (P>0.05) on basal parameters. Moreover, aerobic exercise causes lower red blood cells counts, hemoglobin and hematocrit and increase White blood cells and platelete (P<0.05), However, the rang of lower red blood cells, hemoglobin, hematocrit and increase white blood cells in supplementation group after aerobic exercise low was that placebo group (P<0.05). Tngestion 14-day coenzymQ10 supplementation (with 2/5 g/kg/day) in effective on withe blood cells, hemoglobin and red blood cell indices after that aerobic exercise.