THE EFFECT OF COOLED HEMODIALYSIS FLUID ON THE ADEQUACY OF DIALYSIS: A CLINICAL TRIAL

The use of cold hemodialysis began in 1980 as an attempt to control hypotension during hemodialysis and after these years the researchers realized that Cold hemodialysis not only reduces the periods of hypotension during hemodialysis, but also has other beneficial effects on the adequacy of dialysis, overall health, and quality of life.

This randomized, double-blind, cross-sectional clinical study was carried out at Zanjan University of Medical Sciences. A total of 42 hemodialysis patients were divided into two groups: 20 (first group) and 22 (the second group). Then, the first group received standard hemodialysis (hemodialysis temperature 37 ° C for 4 weeks) and simultaneously the second group received cold hemodialysis (hemodialysis temperature 35 ° C) for 4 weeks, then the type of group hemodialysis was changed. The degree of adequacy of dialysis patients was performed on a monthly basis for three times (before the start of the study, after the first and second 4 weeks) and the data which was available in the hemodialysis computer system of Vali-e-Asr Hospital in Zanjan was calculated using the Ministry of Health's proposed software.

The results showed that mean KTV in cold and standard stage was 1. 71 and 1. 46, respectively and after the second four weeks the mean KTV in cold and standard stage was 1. 69 and 1. 32, respectively. Cold Hemodialysis significantly improved KTV level (P <0. 001). After the first four weeks, the mean URR in the cold and standard phase was 76. 30 and 66. 14, respectively, and after the second four weeks, mean URR in the cold and standard phase was 79. 91 and 69. 20, respectively. Hemodialysis significantly improved URR levels (P <0. 001).

Cold hemodialysis significantly improves the adequacy of hemodialysis.