Comparison of the effect of eight-week training in water, resistance ladder and endurance running on catalase, malondialdehyde, vaspin and insulin resistance in male rats

Increased lipid peroxidation and imbalance of adipokines that affect insulin sensitivity such as vaspin can be effective in the development and progression of atherosclerosis. The aim of present study was comparison and determination of effect of eight-week training in water, resistance ladder and endurance running on catalase (CAT), malondialdehyde (MDA), vaspin and insulin resistance in male rats.

A total of 41 male rats were randomly divided into 5 groups (training in water, resistance ladder, endurance running, sham and control). After two weeks of adapting to the environment and learning the exercises, the training groups exercised for eight weeks. To measure study indices, we used ELISA method and the formula of insulin resistance homeostasis model. One-way analysis of variance and Tukey's post hoc test were used to test the hypotheses.

Eight-week of resistance training significantly increased catalase activity and decreased serum MDA levels more than the other two training methods. Moreover, eight weeks of endurance running and water training significantly reduced serum VASPIN and insulin resistance compared to resistance training (p<0.05).

It seems that resistance training to be superior to the other two training methods in reducing lipid peroxidation, while endurance running and training in water result in greater reductions in VASPIN and insulin resistance than resistance training.