Effect of combined training and subsequent detraining on plasma apelin levels in women with type 2 diabetes

The present study aimed to investigate the effect of twelve weeks of combined training and subsequent eight weeks of detraining on apelin levels in type 2 diabetic women.  

In this experimental study, 30 postmenopausal diabetic women with an age range of 50 to 65 years, overweight (body mass index: 30.42 ± 0.835 Kg / m2) were divided into experimental (n=15) and control (n=15) groups. The experimental group trained for a 12 weeks. Training program (3 sessions per week) according to the combined aerobic program ( 50 to 75  percent of the maximum reserve heart rate) and then resistance training ( 50 to 75 percent of one maximum repetition) and then experienced three weeks of detraining. The apelin level, insulin, fasting blood sugar, insulin resistance, and percent body fat were measured. Data were analyzed by repeated measure ANOVA at a significance level of (p>0.05).

Serum Aplin level in the training group increased significantly at the end of the training period (p = 0.04) and decreased significantly in the detraining period (p = 0.001). Also, these changes compared to the control group was significant (p = 0.016). Fasting blood sugar and insulin levels in the training group compared to the control had a significant decrease at the end of the training and detraining period (p = 0.001).

Combined exercise seems to increase aplin and detraining can partially destroy the positive effects of exercise in this regard.