The effect of 12 weeks of high-intensity interval training and curcumin consumption on glycemic index, adiponectin and lipid profile in obese men with type2 diabetes hyperlipidemia

  Physical exercises and the consumption of medicinal plants with anti-inflammatory properties are one of the most widely used methods to reduce the complications of type 2 diabetes. The aim of this study was to investigate the interactive effect of 12 weeks of high-intensity interval training and curcumin consumption on glycemic index, adiponectin and lipid profile in obese men with type2 diabetes hyperlipidemia.

The current research was a double-blind semi-experimental type. The statistical population included men with type 2 diabetes (mean age 38.76±2.05 years and weight 89.00±2.96 kg), 60 people participated in this research. Subjects were randomly divided into four groups: high-intensity interval training, high-intensity interval training + curcumin, curcumin, and placebo-control. The training intervention was performed three times a week and the consumption daily of curcumin was 2100 mg in three servings of 700 mg, for 12 weeks. Body composition and biochemical indices were measured before and after exercise. One-way ANOVA, two-way factorial ANOVA for repeated measurements and paired samples t test were used to analyze the data.

Interactive effect of exercise and curcumin significantly increased adiponectin (p= 0.010), and significantly decreased glucose (p= 0.0001), insulin (p= 0.0001), HbA1c (p= 0.021), insulin resistance (p= 0.001), TC (p= 0.0001), TG (p= 0.001), LDL (p= 0.002) and HDL (p= 0.011). Exercise alone caused significant changes in all biochemical variables (p<0.05), but curcumin consumption alone did not cause significant changes (P>0.05).

Therefore, high-intensity interval training with curcumin consumption more improved glycemic status and lipid profiles in hyperlipidemia type 2 diabetes men more than the main effect of training and curcumin.