The Effect of Short Time Diet Therapy on Lipid Profiles in Hyperlipidemia

IntroductionHyperlipidemia is a risk factor for cardio vascular diseases (CVD), which may be protected by diet therapy and physical activity. The aim of the present study was the determination of the effects of diet therapy and nutritional education on lipid profiles in hyperlipidemic pateints.Materials and Methods73 subjects out of 183 subjects with hyperlipidemia were selected from our previous research for this semi-clinical trial study. Written consent forms were obtained and 5ml fasting blood sample was collected for TG, T-C, LDL-C and HDL-C analysis before and after intervention. Body composition was assessed using bioelectric impedance (Plusavis 333). All participants received low fat, low cholesterol and high fiber diet including a nutritional guide booklet. Subjects were followed up using phone call every two weeks and data was analyzed using pair T-test and SPSS16.Results45 subjects with average age of 45+8 year completed the study (16 female and 29 male). There was significant reduction in BMI and weight after two months diet therapy (p<0.05). Significant decrease was showed in LDL-C after two month intervention (104.2+2.3 vs. 90.1+2.9, p= 0.001). The study showed borderline reduction in diastolic blood pressure. There was no significant difference for TG, T-C and systolic blood pressure before and after intervention. ConclusionReduction in BMI, weight and LDL-C during short time revealed the effects of diet therapy and nutritional education. Screening for hyperlipidemia and improving public nutritional knowledge using appropriate media to prevent CVD is highly recommended.