جستجوی مقالات مرتبط با کلیدواژه « Insomnia » در نشریات گروه « پزشکی »
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زمینه و هدف
هدف پژوهشگران علوم ورزشی به اوج رساندن عملکرد ورزشکار در رشتههای مختلف ورزشی است. در همین راستا محققان درصدد کشف و شناسایی عواملی هستند که بر عملکرد ورزشکار تاثیرگذارند و این موضوع کاملا پذیرفته شده است که خواب از جمله ضروریات تندرستی است. هدف مطالعه حاضر بررسی اثر 30 ساعت محرومیت از خواب بر پاسخ سطوح اورکسین-A و عملکرد ریوی به یک فعالیت بیهوازی در دانشجویان پسر فعال میباشد.
روش شناسی:
این پژوهش به روش نیمه تجربی و به صورت پیش آزمون و پس آزمون انجام شد. پروتکل به این صورت بود که در موقعیت کنترل، پس از 12 ساعت ناشتایی و 8 ساعت خواب کافی، در موقعیت تجربی بعد از 12 ساعت ناشتایی و 30 ساعت بیخوابی کامل آزمودنیها در محل خوابگاه دانشجویی با شرایط کنترل شده مورد بررسی قرار گرفتند.
یافته هااطلاعات مرتبط به مقایسه پسآزمون و پیشآزمون در دو موقعیت تجربی (محرومیت از خواب) و کنترل (خواب کافی) نشان داد که هورمون اورکسین-A در شرایط محرومیت از خواب نسبت به شرایط استراحتی افزایش معناداری یافته است و این تفاوت در سطح (0.001 p=) معنادار تلقی میشود. هم چنین بیخوابی سبب تغییرات معناداری بر شاخصهای فیزیولوژیکی گردید.
نتیجه گیری30 ساعت محرومیت از خواب سبب افزایش سطوح اروکسین-A گردید که این موضوع نشان دهنده اهمیت خواب شبانه، که یکی از عوامل تاثیرگذار مرتبط با چاقی و اضافه وزن است، می باشد. مخصوصا به وسیله مربیان و ورزشکاران که متعاقب محرومیت از خواب سبب اثر معناداری بر عملکرد آنان میشود، باید بیشتر مورد توجه قرار گیرد.
کلید واژگان: محرومیت از خواب, بی خوابی, چاقی, اورکسین, توان بی هوازی, فعالیت ورزشی, عملکرد ریوی}Background & ObjectivesThe goal of sports science researchers is to maximize the performance of athletes in various sports fields, in this regard, researchers are trying to discover and identify the factors that affect the performance of athletes, and it is completely accepted that sleep is one of the necessities of health. The aim of this study is to investigate the effect of 30 hours of sleep deprivation on the response of orexin-A levels and pulmonary function to an anaerobic activity in active male students.
Materials & MethodsThis research was conducted semi-experimental and in the form of a pre-test and a post-test. The protocol was that in the control position, after 12 hours of fasting and 8 hours of sufficient sleep, in the experimental position after 12 hours of fasting and 30 hours, complete insomnia of the subjects was investigated in the student dormitory with controlled conditions.
ResultsThe information related to the comparison of post-test and pre-test in two experimental situations (sleep deprivation) and control (sufficient sleep) showed that orexin-A hormone increased significantly in sleep deprivation conditions compared to resting conditions and this difference It is considered significant at the (p=0.001) level. Insomnia also caused significant changes in physiological indicators.
Conclusion30 hours of sleep deprivation caused an increase in orexin-A levels, which shows the importance of night sleep, which is one of the influential factors related to obesity and overweight. It should be given more attention, especially by coaches and athletes, who after sleep deprivation has a significant effect on their performance.
Keywords: Sleep Deprivation, Insomnia, Obesity, Orexin, Anaerobic Capacity, Sports Activity, Pulmonary Function} -
اهداف
مسیرهای سبب شناختی مختلفی در بروز افسردگی در کارکنان درمانی نقش دارند. در این مطالعه، تاثیر استرس ادراک شده و بی خوابی بر افسردگی در پرسنل درمانی شهر همدان بررسی شد.
روش کارمطالعه ی حاضر از نوع مقطعی بود که درباره ی کارکنان درمانی بیمارستان های شهید بهشتی و سینا واقع در شهر همدان در سال 1401-1402 اجرا شد. استرس ادراک شده با دو خرده مقیاس درماندگی ادراک شده و خودکارآمدی ادراک شده و بی خوابی و افسردگی با استفاده از پرسش نامه ی اعتبارسنجی شده بررسی شد. تاثیر متغیرها بر افسردگی از طریق تحلیل مسیر بررسی شد.
یافته هاتعداد 235 نفر (35/7 درصد پرستار) از کادر درمان وارد تحلیل ها شدند. جنسیت، سن، افزایش ساعت کار ماهیانه و تعداد شیفت شب در ماه بر افسردگی تاثیر معنی دار داشتند (0/05>P). تحلیل مسیر نشان داد که به جز اثر خودکارآمدی ادراک شده روی بی خوابی، تمامی وزن رگرسیونی استانداردشده برای ارتباط ها از نظر آماری معنی دار بودند (0/05>P). اندازه ی تاثیر درماندگی ادراک شده بر افسردگی نسبت به سایر ارتباط ها قوی تر بود (0/40=وزن رگرسیونی استانداردشده). اثر مستقیم درماندگی ادراک شده و خودکارآمدی ادراک شده بر افسردگی یا اثر غیر مستقیم آن از طریق بی خوابی به عنوان متغیر میانجی، برازش تقریبا مناسبی بر داده ها داشت.
نتیجه گیرییافته های مطالعه بیانگر این است که با اجرای برنامه های مداخله ای و پیشگیرانه به منظور کاهش استرس و بهبود وضعیت خواب، رخداد افسردگی در پرسنل درمانی به میزان درخور توجهی کاهش می یابد.
کلید واژگان: درماندگی ادراک شده, خودکارآمدی ادراک شده, بی خوابی, افسردگی, کادر درمان}ObjectivesVarious causal pathways play a role in the occurrence of depression in healthcare workers. This study aimed to assess the effect of perceived stress and insomnia on depression in healthcare workers using path analysis in Hamadan, Iran.
MethodsIn this cross-sectional study, healthcare workers from Shahid Beheshti and Sina hospitals in Hamedan in 2023 were recruited. Perceived stress with two subscales of perceived helplessness and perceived self-efficacy, as well as insomnia and depression, were investigated using validated questionnaires. The path analysis was applied to assess the association.
ResultsIn total, 235 healthcare workers (35.7% nurses) were included. Gender, age, monthly working hours, and number of night shifts per month had a significant impact on depression (P<0.05). Path analysis demonstrated that except for the effect of perceived self-efficacy on insomnia, all standardized regression weights for relationships were statistically significant (P<0.05). The effect size of perceived helplessness on depression was the strongest compared to other relationships (standardized regression weight = 0.40). The direct effect of perceived helplessness and perceived self-efficacy on depression or insomnia as a mediator had a good fit to the data.
ConclusionAs evidenced by the obtained results, with the implementation of intervention and preventive programs to reduce stress and improve sleep, the occurrence of depression in healthcare workers is expected to decrease significantly.
Keywords: Depression, Health Care Workers, Insomnia, Perceived Helplessness, Perceived Self-Efficacy} -
سابقه و هدف
زنان باردار مستعد ابتلا به اختلالات خواب هستند. عوامل مختلفی می توانند شیوع اختلالات خواب را تحت تاثیر قرار دهند. با توجه به دانش ناکافی در خصوص شیوع بی خوابی و عوامل تعیین کننده ی آن در این زنان، این مطالعه با هدف تعیین شیوع اختلال بی خوابی و عوامل مرتبط با آن در زنان باردار شهر زاهدان انجام شد.
مواد و روش هادر سال 1400، زنان باردار مراجعه کننده به مراکز جامع خدمات سلامت شهر زاهدان وارد این مطالعه ی مقطعی شدند. از طریق چک لیست محقق ساخته، وضعیت جمعیت شناختی، اقتصادی ، اجتماعی و ویژگی های مرتبط با بارداری اندازه گیری شد. اختلال بی خوابی و نشانه ها از طریق پرسش نامه ی اختصاصی شاخص وضعیت خواب تعیین شد. از تحلیل رگرسیون خطی برای تحلیل نتایج استفاده شد. سطح معنی داری آزمون ها 0.05>P در نظر گرفته شد.
یافته هادر مجموع، تعداد 240 زن باردار (با میانگین سنی 6.24 ± 26.30 سال) وارد مطالعه شدند. شیوع کلی بی خوابی برابر با 47.1 درصد بود. شیوع زمان به خواب رفتن و بیدار شدن در طول شب بیشتر از 30 دقیقه به ترتیب، برابر با 56.3 درصد و 72 درصد بود. 57.5 درصد از زنان باردار گزارش کردند که بی خوابی روی عملکرد روزانه ی آن ها تاثیر می گذارد. اختلال بی خوابی در زنان با وضعیت اقتصادی متوسط (بتا=6.22، 0.002=P) و بالا (4.26، 0.04)، با وزن بیشتر از 75 کیلوگرم (4.55، 0.04) و در سه ماهه ی سوم بارداری (3.39 ،0.01) بیشتر است.
نتیجه گیریاختلال بی خوابی در زنان باردار در شهر زاهدان شایع است. زنان باردار از طبقه ی متوسط اقتصادی، آن هایی که اضافه وزن دارند و در سه ماهه ی سوم بارداری هستند، بایستی هدف برنامه های مداخله ای برای کاهش و مدیریت اختلال خواب قرار گیرند.
کلید واژگان: آبستنی, اختلالات خواب, بی خوابی, عوامل تعیین کننده}Background and ObjectivePregnant women are susceptible to sleep disorders due to physiological and hormonal changes. Various demographic, socioeconomic and pregnancy-related factors affect the prevalence of disorders. Knowledge on prevalence of insomnia and related factors in Zahedan is lacking. Therefore, this study aimed to evaluate the prevalence of insomnia and its related factors in pregnant women.
Materials and MethodsThis study was a cross sectional design in Zahedan, Iran during August 2021 and February 2022. Healthy pregnant women referred to urban comprehensive health centers were recruited. Through a researcher-made checklist, demographic, socioeconomic status (SES) and pregnancy-related features were measured. Insomnia was evaluated using Sleep Condition Indicator (SCI) screening tool. Linear regression analysis was used to analyze the data. The significance level of the statistical tests was considered as P <0.05.
ResultsA total, 240 pregnant women (26.30± 6.24 years old) were included. The prevalence rate of insomnia was 47%. Falling asleep and waking up during the night for >30 min were 56.3% and 72.0%, respectively. Daytime functioning impairment had a prevalence rate of 57.5%. Multivariable analysis showed that insomnia disorder is more common in women from the middle (β =6.22, P-value=0.002) and second richest economic status (4.26, 0.04), with a weight of more than 75 kg (4.55, 0.04) and in the third trimester of pregnancy (3.39, 0.01).
ConclusionInsomnia symptoms are prevalent among pregnant women in Zahedan. Pregnant women from the middle and second richest economic status, those who are overweight, and in the third trimester should be the target of intervention and educational programs to reduce and manage sleep disorders.
Keywords: Determinants, Insomnia, Pregnancy, Sleep Disturbances} -
Background
Smartphone is now an inevitable device for the populace, with its use growing progressively worldwide. There is lack of published literature focusing on the consequences of smartphone addiction on middle-aged and older adults in Nigeria. This study investigated the association between smartphone addiction, psychological status, insomnia and pain-related disability of the neck among staff of the College of Medicine, University of Lagos (CMUL).
Materials & MethodsThis study involved the use of cross-sectional survey to investigate 271 (106 females, 165 males) staff of CMUL, Lagos, mean age (45.797±9.28 years) via purposive sampling technique in 2022. Four standard questionnaires were used for data collection; smart phone addiction scale (SAS), depression, anxiety and stress scale (DASS), neck pain disability index (NDI), and insomnia severity index (ISI).
ResultsThe results revealed that 80 (29.5%) staff of college of medicine were addicted to smartphone use. Eleven (4.1%) staff of this college had severe depression, 16 (5.9%) had extremely severe anxiety while nine (3.3%) were severely stressed. Nine (3.3%) participants had clinical insomnia and five (1.8%) had moderate to severe problem with their neck. It was revealed that there was a significant association between smartphone addiction, pain-related disability of the neck (p=0.023), and insomnia (p=0.001). However, no significant association existed between depression (p=0.578), anxiety (p=0.060), stress (0.685), and smartphone addiction level of the participants
ConclusionSmartphone addiction is predominant among staff of CMUL, and it is associated with neck pain-related disability and insomnia.
Keywords: Smartphone, Addiction, Pain, Disability, Insomnia, Depression} -
Background and Purpose
Sleep problems and aggression are common among healthcare workers due to shift work and constant interaction with patients and their relatives. The present study examined the associations between sleep problems, self-regulation, and interpersonal aggression among healthcare workers.
Materials and MethodsIn this cross-sectional study, 400 healthcare workers were selected from four state-run hospitals in Kermanshah City, Iran, using a multi-stage random sampling between March 2021 and March 2022. The sample size was selected using the N>50+8m standard formula. The participants completed several standard scales, including the Pittsburgh sleep quality index, the Berlin questionnaire, the insomnia severity index, the self-regulation questionnaire, and the Buss-Perry aggression questionnaire. The obtained data were analyzed using the Pearson correlation, hierarchical multiple regression techniques, and standardized z scores.
ResultsThe Mean±SD age of the participants was 32.5±8.8 years and 70% were female. All sleep problems, including poor sleep quality, sleep apnea, and insomnia severity, are significantly related to the total score of interpersonal aggression and all its subfactors (P<0.001). The results showed that adding self-regulation to sleep problems to predict aggression greatly reduces the effect of sleep problems, especially the insomnia severity (P<0.001).
ConclusionThe results showed that self-regulation is not only a protective factor for aggression but also indirectly protects against aggression by controlling the severity of insomnia. Because both sleep problems and self-dysregulation are modifiable risk factors for interpersonal aggression, psychological interventions can target these risk factors.
Keywords: Aggression, Insomnia, Protective factors, Self-regulation, Sleep apnea, Sleep quality} -
Background
Sleep disorders are a public health problem, and sleep studies among ethnic groups are few. Therefore, this study aimed to evaluate sleep quality and sleep problems among Iranian people.
MethodsThis cross-sectional study was conducted on 4748 young people aged 18 to 35 (average: 27.58 years) in western Iran during the COVID-19 pandemic. In addition, 60.4% of the participants were men. The data were collected using the Pittsburgh Sleep Quality Inventory (PSQI), the Insomnia Severity Index (ISI), and the Demographic Information Questionnaire and analyzed with SPSS software version 22.
ResultsAbout 44.4% of the participants had unfavorable sleep quality and had sleep problems. Besides, the mean score of sleep problems (measured with PSQI) reported by the participants was 5.68±2.67. The logistic regression analysis showed that the participant’s age, education, marital status, occupation, drug abuse, alcohol consumption, use of mobile phones and the internet, and a history of previous sleep problems accounted for sleep problems during the COVID-19 pandemic.
ConclusionsBased on the results, there was a high prevalence of sleep problems among Iranian young people during the COVID-19 pandemic.
Keywords: COVID-19, Insomnia, Sleep Quality, Sleep Problems, Western Iran} -
بررسی ارتباط کیفیت خواب و سطح قند خون در دانشجویان مقطع کارشناسی علوم پزشکی دانشگاه علوم پزشکی گیلانمقدمه و هدف
خواب یکی از مهم ترین چرخه های شبانه روزی است. اختلالات متابولیک به خصوص دیابت می تواند کمیت و کیفیت خواب را تحت تاثیر قرار دهد. هدف از این پژوهش تعیین ارتباط کیفیت خواب با میزان سطح قندخون است.
روش پژوهش:
در این مطالعه توصیفی-مقطعی، تعداد 613، دانشجوی دختر و پسر به صورت تصادفی خوشه ای طبقه ای از میان دانشجویان دانشگاه علوم پزشکی گیلان در سال 1400 انتخاب شدند. برای جمع آوری اطلاعات از دوپرسشنامه مشخصات فردی (میزان سطح خون) و پرسشنامه استاندارد خواب پیتزبرگ استفاده گردید. داده ها با بهره گیری از نرم افزار SPSS نسخه 16و به کمک روش های آماری توصیفی(فراوانی، میانگین، انحراف معیار) و استنباطی در سطح معناداری 05/0 <p تجزیه و تحلیل شدند.
یافته هانتایج تحقیق نشان داد که بیشترین گروه سنی، سن بیست و یک (45/30 درصد) بود که 65/59 درصد از دانشجویان دختر و بقیه پسر بودند. از نظر وضعیت تاهل 7/57 درصد دانشجویان، متاهل بودند. نیمی از دانشجویان از کیفیت خواب نامناسب رنج می بردند. میانگین مدت زمان خواب نیز نسبت به سایر خرده مقیاسها از درصد بالاتری برخوردار بود. دانشجویانی که کیفیت خواب بدی را گزارش کرده بودند، کنترلی بر روی سطح قند خود نداشته اند. همچنین دانشجویانی که کیفیت خواب خوبی را تجربه نموده بودند، سطح قندشان را خوب کنترل نموده بودند و ارتباط بین کیفیت خواب دانشجو با قند خون شان معنی دار بود.
نتیجه گیریبر اساس نتایج مطالعه می توان گفت کیفیت خواب در ابتلا به دیابت نقش دارد، دانشجویان گروه پزشکی نیز چون کیفیت و کیفیت خواب را به دنبال شب بیداری و کشیک های شبانه تجربه می کنند در معرض ابتلا به دیابت و عوارض آن هستند. بنابراین می توان گفت با آموزش های لازم در این راستا به دانشجویان ازنوسونات قند خون به دنبال اختلالات خوایب تاحدودی پیشگیری نمود.
کلید واژگان: خواب, کیفیت خواب, سطح قند خون, کم خوابی}Journal of Diabetes Nursing, Volume:11 Issue: 3, 2024, PP 2229 -2238IntroductionSleep is one of the most important circadian cycles. Metabolic disorders, especially diabetes, can affect the quantity and quality of sleep. The purpose of this study is to determine the relationship between the quantity and quality of sleep and diabetes.
MethodsIn this descriptive-cross-sectional study, 613 male and female students were randomly selected from the students of Gilan University of Medical Sciences in 1400. To collect information, two questionnaires for personal characteristics (blood sugar level) and the Pittsburgh Sleep Standard Questionnaire (PSQI) were used. The data were analyzed using SPSS version 16 software and descriptive (frequency, mean, and standard deviation) and inferential statistical methods at a significance level of p<0.05.
ResultsThe results of the research showed that the largest age group was 21 (30.45) percent, 59.65 percent of the students were female, and the rest were male. In terms of marital status, 57.7% of students were married. Half of the students suffered from poor sleep quality. The average sleep duration also had a higher percentage than other subscales. Students who reported poor sleep quality did not control their sugar levels. Also, the students who had experienced the quality of sleep had controlled their sugar level well, and the relationship between the quality of the student's sleep and their blood sugar was significant (p =0.001).
ConclusionBased on the results of the study in medical students, it is possible to prevent lack of sleep and its subsequent complications, i.e., increased blood sugar levels and diabetes, by teaching sleep hygiene and changing incorrect beliefs and habits despite the presence of night wakings and night watches
Keywords: Sleep, Sleep quality, Blood sugar levels, Insomnia} -
Introduction
Insomnia in older people results from aging and declining body function. However, no studies have identified the proper therapy to reduce insomnia in older adults.
ObjectiveThis study aimed to examine the complementary therapies commonly used to lessen insomnia in older adults.
Materials and MethodsA systematic review was conducted based on PRISMA (the preferred reporting items for systematic reviews and meta-analyses), and quantitative and randomized controlled trials were searched in PubMed, Science Direct, Google Scholar, Lilacs, SciELO, DOAJ, ProQuest, and GARUDA. The methodological quality of the included studies was assessed using the EPHPP QAT (the effective public health practice project for quality assessment tool) for quantitative studies. Only studies of moderate and strong quality were included.
ResultsWe analyzed 11 studies with a sample of 2495 older people. The significance of therapeutic effects on elderly insomnia had a strong influence with a P of 0.05 and Cohen’s kappa of 0.80 in four studies. We identified 11 articles that found complementary therapies appropriate and recommended in reducing insomnia in older adults, including Tai Chi, cognitive behavior therapy, lavender aroma, and digital cognitive therapy. The results of the insomnia score were more than 50% positive changes, without adverse effects, including improvement in sleep efficiency (57%), total sleep time (60%), and insomnia rating scale score (75%).
ConclusionThe application of complementary therapy has put forward alternative treatments for older adults to reduce insomnia problems, improve their quality of life, and enhance the qualifications of nurses in other applied fields.
Keywords: Complementary therapy, Insomnia, Sleep disorders, Older adults} -
Background and Objective
Insomnia is the most common sleep problem which is associated with cortical over-excitation. Transcranial direct-current stimulation (tDCS) potentially modifies insomnia-related cortical state. There-fore, we tested the hypothesis that insomnia severity can be modulated by tDCS.
Materials and MethodsThe current study was conducted with a pretest-posttest design and a control group. A total of 32 women with insomnia were randomly categorized into an intervention group (active stimulation) and a control group (sham stimulation). In the intervention group, tDCS was used with an intensity of 2mA for 20 to 30 minutes during 12 sessions (3 times a week). Anodal stimulation was performed on the left primary motor cortex (M1) and cathodal stimulation was performed on the right dorsal lateral prefrontal cortex (DLPFC). The control group received sham stim-ulation for 20 to 30 minutes during 12 sessions (3 times a week). All participants were evaluated before and after the intervention using the Insomnia Severity Index (ISI) and Positive Affect and Negative Affect Schedule (PANAS).
ResultsThe results of univariate analysis of covariance (ANCOVA) and multivariate analysis of covariance (MANCOVA) showed a significant difference between the tDCS group and the sham group in terms of reduction in the severity of insomnia. We also observed that positive affect increased and negative affect decreased following insomnia treatment (P ≤ 0.005).
ConclusionThe results of our study indicated that performing our designed tDCS protocol for treating insomnia can be effective in treating insomnia and improving positive and negative affect.
Keywords: Transcranial direct current stimulation, Insomnia, Motor cortex, Dorsolateral prefrontal cortex} -
مجله دانشکده پزشکی دانشگاه علوم پزشکی مشهد، سال شصت و ششم شماره 5 (پیاپی 191، آذر و دی 1402)، صص 1150 -1165
اختلالات خواب، شایع ترین شکایات رفتاری در کودکان می باشد. علایم و عوارض خواب ناکافی در کودکان با بزرگسالان متفاوت بوده و ممکن است به صورت تغییرات خلقی، فعالیت ها و بیش از حد کوتاه شدن دامنه توجه و اختلالات عصبی شناختی خود را نشان دهد. پژوهش حاضر با هدف بررسی اختلال خواب در کودکان مراجعه کننده به درمانگاه اطفال و رابطه آن با بی-خوابی مادر در بیمارستان بهارلو در سال 98-1397 انجام شد.این پژوهش مقطعی از نوع تحلیلی-توصیفی است. جامعه آماری شامل کودکان 2 تا 12 سال مراجعه کننده به بیمارستان بهارلو است که با در نظر گرفتن معیارهای ورود 303 نفر به عنوان نمونه وارد مطالعه گردید. ابزار گردآوری اطلاعات شامل؛ پرسشنامه ی BEARS جهت بررسی اختلال خواب اطفال و پرسشنامه ی ISI برای بررسی بی خوابی مادران استفاده گردید. داده ها با استفاده از شاخص های آمر توصیفی و آزمون آماری T-test مورد تجزیه و تحلیل قرار گرفت.یافته ها نشان داد که از بین کودکان 2 تا 12 سال74 مادر بر اساس پرسشنامه خواب دچار بی خوابی بودند که از لحاظ آماری رابطه معنی داری بین بی خوابی مادر بر اساس ISI و جنسیت کودکان مادران وجود داشت به طوری که بین این تعداد 36 مادر دارای کودک دختر و 38 مادر دارای فرزند پسر بودند. اما مادران بی خواب از نظر درصدی در میان مادران کودکان دختر بیشتر بودند (44.4 درصد) (05/0p<). همچنین رابطه معنی داری بین کودکانی که هنگام خواب شبانه در رفتن به رختخواب مشکلی دارند و دارای مادر بی خواب هستند، وجود داشت.
کلید واژگان: اختلال خواب, بی خواب, اطفال, مادر}Background and AimSleep disorders are the most common behavioral complaints in children. Signs and symptoms of inadequate sleep in children are different from those in adults and may manifest as mood swings, activities, and excessive attention span and neurological disorders. The aim of this study was to investigate sleep disorders in children referred to pediatric clinics and its relationship with maternal insomnia in Baharloo Hospital in 1397-98.
MethodThis is a cross-sectional study of analytical-descriptive type. The statistical population includes children aged 2 to 12 years referred to Baharloo Hospital who were included in the study as a sample by considering the inclusion criteria of 303 people. Data collection tools include; The BEARS questionnaire was used to assess sleep disorders in children and the ISI questionnaire was used to assess maternal insomnia. Data were analyzed using descriptive statistics and T-test.
ResultsThe results showed that among children aged 2 to 12 years, 74 mothers had insomnia according to the sleep questionnaire. The mother had a daughter and 38 mothers had a son. But insomnia mothers were higher in percentage among mothers of female children (44.4%) (p <0.05). There was also a significant relationship between children who have trouble going to bed at night and who have an insomniac mother. Among sleepless mothers (n = 74), 27 children (36.5%) had difficulty going to bed at night, which was higher in terms of both number and percentage of children of mothers with normal sleep (p <0.05). .
Keywords: sleep disorder, insomnia, Children, Mother} -
مقایسه میزان قند خون، کورتیزول و انسولین افراد ورزشکار و غیر ورزشکار پس از یک شب محرومیت از خوابمقدمه
بی خوابی و اختلالات خواب با کاهش سلامت جسمانی و روانی و کیفیت زندگی در ارتباط است. هدف از مطالعه حاضر بررسی تاثیر محرومیت از خواب بر میزان قند خون، کورتیزول و انسولین افراد ورزشکار در مقایسه با افراد غیرورزشکار بود.
روش کاردر این مطالعه نیمه تجریی 14 مرد سالم در دو گروه ورزشکار (7 نفر) و غیر ورزشکار (7 نفر) شرکت داشتند. برای آزمودنی های هر دو گروه یک شب بی خوابی (8ساعت) اعمال شد. با توجه به اهداف پژوهش از همه آزمودنی ها طی دو مرحله نمونه گیری خونی گرفته شد. داده ها با استفاده از آزمون t وابسته در مقایسه درون گروهی و t مستقل برای مقایسه بین گروهی در سطح معناداری 5 درصد بررسی شدند. در انجام پژوهش، اصول بیانیه هلسینکی، راهنمای عموم اخلاق در پژوهش های دارای آزمودنی انسانی و مقررات حاکم بر آن رعایت شده و کد اخلاق به شناسه (LU.ECRA . 2022. 21) توسط کمیته اخلاق دانشگاه لرستان صادر شد.
یافته هااعمال بی خوابی منجر به تفاوت معنی داری بین قندخون و میزان انسولین افراد ورزشکار و غیر ورزشکار در مواجه با یک نشد (p≤0.05). همچنین بی خوابی موجب تفاوت معنی داری در میزان کورتیزول بین دو گروه ورزشکار و غیرورزشکار نشد (p≤0.05).
نتیجه گیریبه نظر می رسد تغییرات میزان قندخون، کورتیزول و انسولین با طول مدت بی خوابی رابطه دارد و در بی خوابی های کوتاه مدت و مقطعی تحت تاثیر قرار نمی گیرند.
کلید واژگان: ورزشکار, بی خوابی, قندخون, کورتیزول, انسولین}Comparison of blood sugar, cortisol and insulin levels in athletes and non-athletes after one night of sleep deprivationIntroductionInsomnia and sleep disorders are related to a decrease in physical and mental health and quality of life. The purpose of this study was to investigate the effect of sleep deprivation on blood sugar, cortisol and insulin levels in athletes compared to non-athletes.
MethodsIn this semi-experimental study, 14 healthy men participated in two groups of athletes (7 people) and non-athletes (7 people). One night of sleeplessness (8 hours) was applied to the subjects of both groups. According to the objectives of the research, blood samples were taken from all the subjects in two stages. The data were analyzed using the dependent t test for intra-group comparison and independent t test for inter-group comparison at a significance level of 5%. In conducting the research, the principles of the Declaration of Helsinki, the general guidelines for ethics in research with human subjects and the regulations governing it were observed and the code of ethics was issued by the ethics committee of Lorestan University.
FindingsInsomnia did not lead to a significant difference between the blood sugar and insulin levels of athletes and non-athletes when faced with a (p≤0.05). Also, insomnia did not cause a significant difference in the amount of cortisol between two groups of athletes and non-athletes (p≤0.05).
ConclusionIt seems that changes in blood sugar, cortisol and insulin are related to the duration of insomnia and are not affected in short-term and intermittent insomnia.
Keywords: Athlete, Insomnia, Blood Glucose, Cortisol, Insulin} -
Objective
Premenstrual syndrome and primary dysmenorrhea are common gynecological complaints that are associated with psychological disorders. There is increasing evidence for the neuroprotective properties of curcumin, a polyphenolic natural product. This study aimed to assess the effects of curcumin on sleep complications in women with premenstrual syndrome and dysmenorrhea.
Materials and MethodsThis triple-masked, placebo-controlled clinical trial comprised 124 patients with both premenstrual syndrome and dysmenorrhea. Participants were randomly assigned to curcumin (n=57) or control (n=60) groups. Each participant received one capsule containing either 500 mg of curcumin plus piperine or placebo, daily, from 7 days before until 3 days after menstruation for three consecutive menstrual cycles. Insomnia and sleepiness were assessed using standard questionnaires.
ResultsScores for insomnia and daytime sleepiness were directly correlated with the Premenstrual Syndrome Screening Tool (PSST) score (p<0.05), but not with the visual analogue scale (VAS) score at baseline (p>0.05). There was a non-significant reduction in insomnia and sleepiness scores in both curcumin and placebo groups after the study intervention. Whilst, improvement rate of insomnia status, daytime sleepiness severity, short sleep duration and difficult sleep initiation was not statistically significant between the curcumin and placebo groups.
ConclusionCurcumin does not significantly affect sleep disorders in young women with premenstrual syndrome and dysmenorrhea.
Keywords: insomnia, Menstruation, Sleepiness, Turmeric} -
Background & Aim
The emergence of COVID-19 has created fears, worries, and anxiety among individuals worldwide. This study aimed to describe the prevalence of mental health problems (fear, stress, anxiety, depression, and insomnia) and their contributing factors among undergraduate nursing students in Oman two years after the start of the pandemic.
Methods & Materials:
A cross-sectional study was employed for this study. The questionnaire was distributed electronically via Qualtrics® Online survey software. It consisted of items relating to detailed demographics, background history, and standard scales, including the Fear of COVID-19 Scale, the Perceived Stress Scale, the Hospital Anxiety and Depression Scale, and the Insomnia Severity Index.
ResultsThe sample comprised 548 nursing students. The participants had a mean FVC-19 score of 16.39, with a standard deviation of 6.04. The overall prevalence of stress, anxiety, depression, and insomnia among nursing students was 94%, 70%, 53%, and 38%, respectively. There was a significant relationship between fear of COVID-19 (p< 0.05) and stress, anxiety, depression, and insomnia.
ConclusionFear of COVID-19, stress, anxiety, depression, and insomnia pose notable challenges for undergraduate nursing students. Identifying these mental health issues early is crucial as well as introducing preventive and supportive interventions tailored to the specific contributing factors. This is essential to mitigate the potential for more severe psychological consequences among nursing students.
Keywords: COVID-19, nursing students, fear, stress, anxiety, depression, insomnia} -
مجله دانشکده پزشکی دانشگاه علوم پزشکی تهران، سال هشتاد و یکم شماره 3 (پیاپی 266، خرداد 1402)، صص 197 -209زمینه و هدف
بی خوابی شایعترین اختلال خواب است که با بیشبرانگیختگی قشری همراه می باشد. تحریک جریان مستقیم فراجمجمه ای (tDCS) به طور بالقوه حالت قشری مرتبط با بی خوابی را اصلاح می کند. ما فرض کردیم با به کارگیری tDCS می توان شدت بی خوابی و علایم عاطفی ناشی از آن را بهبود بخشید.
روش بررسیمطالعه حاضر طرح آزمایشی با پیش آزمون-پس آزمون با گروه کنترل بود که از تیر تا آذر 1401 در مرکز تحقیقات اختلالات خواب شغلی بیمارستان بهارلو و کلینیک خواب بیمارستان امام خمینی تهران انجام شد. 32 زن مبتلا به بی خوابی به صورت تصادفی در گروه های آزمایشی و کنترل قرار گرفتند. تحریک فعال جریان مستقیم فراجمجمه ای شامل تحریک آنودال ناحیه گیجگاهی فوقانی (STG) چپ و تحریک کاتودال قشر پیش پیشانی پشتی-جانبی (DLPFC) راست و قشر حرکتی ثانویه (SMA) چپ با شدت دو میلی آمپر به مدت 30 دقیقه، در 12 جلسه (هفته ای سه بار) برای گروه آزمایشی اجرا شد. در گروه کنترل نیز تحریک ساختگی به مدت 30 دقیقه در طی 12 جلسه (هفته ای سه بار) انجام گرفت. شرکت کنندگان پیش و پس از مداخله توسط شاخص شدت بی خوابی (ISI) و مقیاس عاطفه مثبت و منفی (PANAS) موردارزیابی قرار گرفتند.
یافته هانتایج نشان داد درمان الکتریکی مستقیم فراجمجمه ای بر شدت بی خوابی و عاطفه مثبت و منفی موثر بوده است (001/0>P، 19/87F=). مقدار این تاثیر (eta2) در متغیر شدت بی خوابی، عاطفه منفی و مثبت به ترتیب 64/0، 34/0 و 6/0 می باشد.
نتیجه گیریبر طبق نتایج، پروتکل درمانی طراحی شده ما برای درمان بی خوابی، به طور معناداری شدت بی خوابی را در زنان مبتلا به بی خوابی مزمن کاهش داد و علایم خلقی آنها را بهبود بخشید.
کلید واژگان: بی خوابی, خلق, تحریک جریان مستقیم فراجمجمه ای (tDCS)}BackgroundInsomnia is the most common sleep disorder that is associated with cortical hyperexcitability. Potentially transcranial direct current stimulation (tDCS) modifies the cortical state related to insomnia. Therefore, we hypothesized that by using tDCS the intensity of insomnia can be reduced, followed by improvement of the mood symptoms.
MethodsThis study was an experimental design with a pre-test and post-test with a control group. The statistical sample included 32 females with chronic insomnia that were randomly divided into an experimental group (active stimulation) and a control group (sham stimulation). Transcranial direct current with an intensity of 2 mA was applied for 30 minutes during 12 sessions (three times in the week) in the active stimulation group. In this protocol, anodal stimulation of left Superior temporal gyrus (STG) and cathodal stimulation of right dorsolateral prefrontal cortex (DLPFC) and left secondary motor cortex (SMA). In the control group, sham stimulation was performed for 30 minutes during 12 sessions (three times in the week). The participants were evaluated before and after of the intervention using the Insomnia Severity Index (ISI) and Positive and Negative Affect Scale (PANAS).
ResultsThe findings of this research showed that the application of transcranial direct current stimulation was effective in reducing the severity of insomnia and improving positive and negative affect (P<0.001, F=19.87). The value of this effect (eta2) in the severity of insomnia, negative mood and positive mood is 0.64, 0.34 and 0.6 respectively.
ConclusionThe results of the present study showed that the implementation of our designed tDCS protocol for the treatment of insomnia, significantly reduced the intensity of insomnia in women with chronic insomnia and improved their mood symptoms.
Keywords: insomnia, mood, transcranial direct current stimulation (tDCS)} -
پیش زمینه و هدف
ریتم های شبانه روزی فرآیندهایی طبیعی هستند که چرخه خواب وبیداری را تنظیم می کنند و تقریبا هر 24 ساعت تکرار شده و توسط یک ساعت شبانه روزی درونی کنترل می شوند. عملکرد نادرست سیستم ساعت شبانه روزی باعث اختلال در الگوی طبیعی خواب می شود. تنظیم مولکولی این سیستم توسط تعدادی از ژن های ساعت انجام می شود که مهم ترین آن ها ژن CLOCK است و یک فاکتور رونویسی را کد می کند که نقش اساسی در تنظیم ساعت شبانه روزی مولکولی دارد. در این مطالعه پلی مورفیسم جایگاه rs1801260 ژن CLOCK در بیماران ایرانی مبتلا به اختلال بی خوابی موردبررسی قرار گرفت.
مواد و روش هادر این مطالعه، 60 نمونه خون از افراد دارای مشکلات عمقی بی خوابی، ناتوانی در کنترل خواب و خواب نامنظم به عنوان گروه بیمار و 60 نمونه از افراد بدون هیچ گونه سابقه بی خوابی و یا اختلال در خواب به عنوان گروه کنترل به دست آمد. سپس استخراج DNA انجام شده و بررسی پلی مورفیسم با روش ARMS-PCR و با پرایمرهای اختصاصی برای آلل های طبیعی و موتانت انجام شد و نتایج بررسی گردید.
یافته هابر اساس نتایج، 50درصد بیماران دارای ژنوتیپ GG، 7/36درصد ژنوتیپ AG و 3/13درصد ژنوتیپ AA بودند. در گروه کنترل نیز فراوانی ژنو تیپ های GG، AG و AA به ترتیب معادل 30درصد، 7/26درصد و 3/43درصد بوده است. همچنین این پلی مورفیسم به طور معنی داری با اختلال بی خوابی در بیماران مرتبط است (p<0.05) و با جنسیت، سن و سبک زندگی بیماران ارتباط معناداری ندارد.
بحث و نتیجه گیریاین یافته ها نشان می دهد که پلی مورفیسم rs1801260 و آلل G در این جایگاه ارتباط معنی داری با اختلال خواب داشته و به نظر می رسد که نقش مهمی در بروز این بیماری در جمعیت ایرانی دارد. ازاین رو بررسی ژن CLOCK در افراد بیمار یا مستعد می تواند برای پیشگیری و درمان موثر بیماری کمک کننده باشد.
کلید واژگان: ریتم شبانه روزی, ژن CLOCK, بی خوابی, پلی مورفیسم, rs1801260}Background and AimsCircadian rhythms are natural processes that regulate the sleep-wake cycle and are repeated approximately every 24 hours and controlled by an internal circadian clock. Incorrect functioning of the circadian clock system disrupts the normal sleep pattern. The molecular regulation of this system is done by several clock genes, the most important of which is the CLOCK gene that encodes a transcription factor that plays a central role in regulating the molecular circadian clock. In this study, the rs1801260 polymorphism of the CLOCK gene was investigated in Iranian patients with insomnia.
Materials and methodsIn this study, 60 blood samples were collected from people with profound problems of insomnia, inability to control sleep and irregular sleep as the patient group and 60 samples from people without any history of insomnia or sleep disorder as the control group. Then DNA was extracted and rs1801260 polymorphism was assessed by ARMS-PCR using specific primers for normal and mutated alleles and the results were analyzed.
ResultsAccording to the results, 50% of patients had GG, 36.7% had AG and 13.3% had AA genotype. In the control group, the frequency of GG, AG and AA genotypes was 30%, 26.7% and 43.3%, respectively. Also, this polymorphism is significantly associated with insomnia in patients (p<0.05) and has no significant relationship with gender, age and lifestyle of patients.
ConclusionThese findings show that the rs1801260 polymorphism and the presence of the G allele in this position have a significant relationship with sleep disorder and it seems to play an important role in occurrence of insomnia in the Iranian population. Therefore, checking the CLOCK gene in patient or susceptible people can be helpful for effective prevention and treatment of the disease.
Keywords: Circadian Rhythm, CLOCK Gene, Insomnia, Polymorphism, rs1801260} -
Background and Objective
In previous studies, multiple interventions to improve sleep quality were suggested in students with insomnia based on different results. The present study aimed to investigate the effects of combined binau-ral beat treatment on improving sleep quality in students with insomnia.
Materials and MethodsThis was a randomized clinical trial, which included all students living in Neyshabur, Khora-san Razavi Province, Iran, in 2020. In terms of inclusion criteria, 34 students (12 women) were assigned randomly into two control (n = 17) and experimental groups (n = 17). A combined binaural beat treatment (α, θ, and δ) and sleep hy-giene guidelines were given to the experimental group, but the control group only received the same sleep hygiene guidelines. Insomnia Severity Index, Sleep Hygiene Index, and Pittsburgh Sleep Quality Index were research instru-ments for this purpose. The results were analyzed with SPSS software.
ResultsThe effect of the combined binaural beats on ISI (F = 31.16, P < 0.001), sleep hygiene (F = 39.15, P < 0.001), and sleep quality (F = 14.15, P < 0.001) of students with insomnia was apparent during multivariate analysis of covari-ance (MANCOVA). The highest and lowest effects on the total value of sleep (effect size = 0.58) and the SHI (effect size = 0.35) were achieved by combined binaural beat treatment.
ConclusionThe combined binaural beats (α, θ, and δ) improve total sleep quality, sleep hygiene, and ISI of students with insomnia. Besides, such a treatment can be utilized as a modern non-invasive intervention.
Keywords: Insomnia, Sleep, Sleep hygiene, Students} -
Background & aim
Restless leg syndrome (RLS) is a frequent sensory dyskinesia disorder of the nervous system and a cause of disability in several aspects. This study aimed to determine the relationship between RLS and mood complications, menstrual patterns, and its associated symptoms among young women.
MethodsThis cross-sectional study was undertaken on 118 female university students in Birjand, Iran, from December 2019 to January 2020 using a multistage cluster sampling method. The degree of RLS was assessed using the International RLS Severity Scale. The severity of PMS was characterized via the Premenstrual Syndrome Screening Tool (PSST). Neuropsychological performance of participants was evaluated. Data analysis was performed by SPSS software (version 16.0).
ResultsOf 118 participants, 29.7%, 32.2%, 27.9%, and 10.2% of them were not affected by RLS or suffered from mild, moderate, or severe types of RLS, respectively. The subjects with RLS had a significantly lower duration of their menstruation cycle and higher PSST scores compared to those without it. Subjects with different severities of RLS scored higher for the severity of depression, anxiety, stress, insomnia, and sleepiness than normal women (P<0.01). The RLS score was a significant factor related to the scores for cognitive abilities (β=-0.33; P=0.022), depression (β=0.32; P=0.001), anxiety (β=0.24; P=0.003), stress (β=0.44; P<0.001), quality of life (β=-0.23; P<0.001), insomnia (β=0.21; P=0.001), sleepiness (β=0.15; P=0.014) and PSST (β=0.28; P=0.019).
ConclusionIn the absence of health management, RLS is potentially associated with depression, anxiety, sleep disruption, cognitive impairment, decreased quality of life, and menstrual problems.
Keywords: Restless leg syndrome, stress, Menstruation, insomnia, Dysmenorrhea} -
Subacute thyroiditis is an uncommon thyroid disease which usually occurs after a viral infection. During COVID-19 pandemics, several subacute thyroiditis cases were identified during or after COVID-19. Due to their similar manifestations and high prevalence of COVID-19, subacute thyroiditis might be neglected if the clinicians do not keep it in mind. In this care report, we present a missing patient with SARS-COV-2 infection and subacute thyroiditis which was not suspected until the latent phase of the disease.The patient report can be a re-emphasis on the importance of clinical examination and especially paying attention to palpation of the thyroid gland.
Keywords: SARS-COV-2, Thyroid, COVID-19, Subacute thyroiditis, Neck pain, Insomnia} -
The prevalence of psychiatric disorders namely depression, anxiety, and sleep disturbances has been increased worldwide, particularly during the COVID-19 pandemic. In this regard, the interest of recent investigations is moved toward phytomedicines and bioactive substances derived from natural sources. Although Tilia platyphyllos Scop. contains high amounts of phenolic compounds such as quercetin, kaempferol, and catechin, there is no study on the possible effects of its extract on psychological disorders. The present study was carried out to determine the antidepressant-like, anxiolytic, and sedative-hypnotic effects of the hydroethanolic extract of T. platyphyllos leaves using forced swimming test (FST), tail suspension test (TST), elevated plus maze test (EPMT), pentobarbital-induced loss of righting reflex test and open field test (OFT). Following the ethanolic extraction of T. platyphyllos leaves, the extraction yield was 14% and the total phenolic and total flavonoid contents were found to be 135.23 ± 0.14 mg gallic acid equivalent/g dry extract and 19.02 ± 0.03 mg rutin equivalent/g dry extract, respectively. Both FTS and TST revealed a significant antidepressant-like activity for the tested extract at 400 mg/kg compared to the control group. In addition, the anxiolytic activity of the extract was proven through OFT and EPMT in the same dose. Finally, T. platyphyllos extract at 200 mg/kg and 400 mg/kg significantly increased the sleeping time when compared to the control group reflecting its potential hypnotic activity. Co-administration of T. platyphyllos extract at 400 mg/kg and flumazenil as the GABA-A receptor antagonist decreased the sleeping time but the observed effect was not statistically significant. Therefore, we cannot completely rule out the involvement of GABA-A receptors in the hypnotic activity of the extract. The biological results presented here led us to conclude that T. platyphyllos extract can be a prominent source of antidepressant, anxiolytic and hypnotic agents. Probably, the main phenolic compounds of T. platyphyllos such as quercetin, kaempferol, and catechin are involved in the observed effects. However, there is still a great need for additional investigations on the exact mechanisms.
Keywords: Anxiety, Depression, Flavonoid, Insomnia, Mice, Phenolic content, T. platyphyllos} -
Background
Insomnia affects the daily activities of the sufferers and reduces attention and memory. Cognitive behavioral therapy is an expensive treatment and is not applicable to all patients, and long‑term treatment with sleep medication can have side effects such as drug dependency. As an alternative form of non‑pharmacological treatments, the effect of exercise therapy on improving the symptoms of insomnia is addressed in the current study.
MethodsA total of 32 patients diagnosed with insomnia participated in the study, from which 16 received combined resistance‑aerobic exercise therapy. The rest of the patients comprised the control group. The intervention group went through a 12‑week intervention in the form of aerobic exercise for 3 days a week and resistance training for another 3 days a week. Patients’ sleep quality was assessed by the Pittsburgh test before and after the intervention.
ResultsThe results showed that combined aerobic‑resistance exercise can improve sleep quality in patients with insomnia as well as increase subjective sleep quality and actual sleep duration, and decrease daytime dysfunction due to sleeping problems.
ConclusionsThis study shows that, along with other insomnia treatments, exercise can improve the sleep quality of patients.
Keywords: Aerobic exercise, insomnia, resistance exercise, sleep, sleep quality}
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