مجله تحقیق در علوم دندانپزشکی
سال بیستم شماره 3 (پیاپی 77، پاییز 1402)

 Dental implants are one of the most accepted methods for tooth replacement, function and esthetic improvement. Sinabionic dental implant (Nikkasht Asia, Iran) was manufactured by grade 5 titanium alloy with Sandblasted, large grit, Acid-etched (SLA) and hydrophilic surface with a porosity of 1.2 to 1.8 µm. The aim of this study was clinical and radiological evaluation of Sinabionic implant system at 3, 6 and 12 month intervals after implant placement surgery.

 After obtaining written consent from the patients, 53 Sinabionic implants (Niktash Asia, Iran) were evaluated in this study.  Pocket depth, bleeding on probing, pus, mobility and pain were evaluated in clinical examination and bone resorption in mesial and distal were assessed in the radiographic examination by one sample t test. 

 5 failures were observed of 53 implants and 32 implants were successful according to the accepted criteria, which includes 60.4% and the Survival rate of these implants was reported to be 90.6%.

  Clinical and radiographic evaluations of Sinabionic implants indicated success and survival rate less than the accepted standard range. It is strongly recommended that the structure (micro and macro geometry) and surface quality of the implant be modified.

Recently, MTA-based sealers have been introduced to achieve biological properties and tissue compatibility and high sealing strength. However, few studies are available on the effect of bioceramic-based sealers, including CeraSeal, on fiber post bonding strength. This study was conducted with the aim of investigating the effect of the type of endodontic sealer on the bond strength of the fiber post to the root canal in a laboratory environment at the Faculty of Dentistry of Azad University of Tehran in 2021.

 In this laboratory and in vitro study, a total of 30 maxillarysingle canal anterior teeth that were extracted due to periodontal reasons were included in the study, Cereseal, MTA Fillapex, Ah plus sealers were randomly placed in 3 groups of 10. The canals were filled with gutta-percha (Ariadent, Tehran, Iran) by cold lateral compression method. The samples were kept at 37°C and under 100% relative humidity for 7 days. The gutta percha was removed from the root canals by piezoreamer number 2 so that at least 5 mm of gutta remained at the end of the canals. Then the space of the post was prepared for the RTD fiberpost by special drills, and at the end the fiberposts were cemented using panavia f2 dual cure resin cement.24 hours after placing the samples in incubator, a diamond disk was used to prepare 1 mm thick cross-sections from the coronal third of the samples in disk form. Finally, the bond strength was measured by push-out technique in each tooth piece with the formula P=F/A. For data analysis, one way Anova test was used in SPSS version 22 software.

 The results showed that there is a significant difference in the bond strength of the fiber post to the root canal based on the type of sealer. The bond strength of the fiber post to the root canal in AH plus sealer was higher than MTA fillapex and Ceraseal sealer (P < 0.0001), but there was no significant difference in the bond strength of fiber post to the root canal in MTA fillapex and Ceraseal sealer (P= 0. 5).

 The bond strength of fiber post to root canal in epoxy resin based sealers is higher than MTA and bio ceramic based sealers.

Background and Aim :

 Candida albicans and Streptococcus mutans are common microorganisms that cause infection in the form of caries and candidiasis.The aim of this study was to compare the antifungal and antibacterial effects of clove extract and fluconazole solution on Streptococcus mutans and Candida albicans.

 In this laboratory study were used Streptococcus mutans (ATCC 35668) and Candida albicans (ATCC 5027). Clove extract was prepared in concentrations of 6/25 -12/5 -25-50 -100. Then 10 mg of fluconazole powder was dissolved in methanol and brought to the desired volume and inoculated separately into wells in Sabouraud Dextrose Agar culture medium for Candida albicans and Mitis Salivarius Agar  for Streptococcus mutans. After 24-48 hours, the minimum inhibitory concentration and diameter of their growth inhibition zone were determined. The data were analyzed using Kruskal-Wallis and Mann-Whitney tests.

 The mean diameter of the non-growth halo of Streptococcus mutans in the vicinity of clove extract had a significant difference (p<0.001). And in fluconazole solution, no growth halo diameter was observed against Streptococcus mutans bacteria. The halo diameter of Candida albicans fungus was not observed in different concentrations of clove extract. But in the solution of fluconazole, there was an average diameter of the halo of non-growth against this fungus.

Clove extract has high antibacterial activity, but no evidence of antifungal effect was found in clove extract.

 Dental caries is the most widespread chronic disease.There are several medical procedures to prevent and control its extension.Based on side effects of chemical products and effectiveness of nanoparticles, this study done inorder to evaluate the antimicrobial effect of silver nanoparticles produced by green synthesis using diospyros extract on oral bacteria.

 In this experimental study the diospyros extract was produced by Maceration procedures at Zanjan university of medical sciences in 2019 .The effect of silver nanoparticles produced by green synthesis was determined on various concentrations of Enterococcus, Streptococcus Mutans, Streptococcus Subrinus, Streptococcus Salivarius, Lactobacillus micro organisms by cap plate method. Minimum Inhibitory Concentration (MIC) and Minimum Bacterial Concentration (MBC) factors was determined. The datas was imported to the SPSS 24 program and analysed by Wilcoxan , Mann-Withny, Kruskal-wallis tests.

.the MIC factor for streptococcus mutans, enterococcus, streptococcus salivarius was determined 1024 μgr⁄mL  and for streptococcus subrinus and lactobacillus 512 μgr⁄Ml. Although the antimicrobial resistance due to MBC factor is decreased from Enterococcus  to, streptococcus mutans, lactobacillus, streptococcus salivarius, streptococcus subrinus sequentially (P=0.014). The finding showed that the antimicrobial resistance of streptococcus mutans, enterococcus, streptococcus salivarius due to MIC factor is more than streptococcus subrinus and lactobacillus.

 The results showed the bacteriostatic effect of silver nanoparticles produced by green synthesis using Diospyros extract on oral pathogens.due to herbal source an being native, maybe this plant can be useful to produce mouthwashes and toothpastes.

 Microleakage is one of the most common problems in bonding systems. The ingress of micro-organisms and oral fluids through microscopic spaces between restoration and tooth structure is known as microleakage. The aim of this research was to compare the Microleakage of three types of bondings in CLV composite cavities.

 In this experimental study, CLV cavities were prepared in 2*3*2 mm on the buccal surfaces of 45 premolars, with the occlusal margin on enamel and gingival margin on cementum 1 mm below CEJ. The teeth were divided into 3 groups of 15 each. The cavities were treated by Futurabond DC, Solo Bond M, and Futurabond NR (Voco, Germany). Grandio composite (Voco, Germany) was used to restore the cavities. After thermocycling, the samples were immersed in silver nitrate for 24 h and then in developer solution for 6 h. samples evaluated under a stereomicroscope after buccolingual sectioning. Kruskal Wallis test was used for statistical analysis.

 This study revealed that in the gingival area, Solo Bond M had type 1 microleakage in 80% of the cases (dye penetration up to 1/3 of the cavity wall) and type 2 microleakage in 20% (dye penetration up to 2/3 of the cavity wall). Futurabond DC bond had no microleakage in 6.7% of the cases, type 1 in 66.7%, and type 2 in 26.7% of the cases. Futurabond NR bonding had no microleakage in 6.7%, type 1 in 33.3%, and type 3 in 60% of cases (dye penetration in all cavity walls without axial wall involvement ). There was no statistically significant difference in the microleakage at the occlusal margins between 3 groups (P=0/071)

 the amount of microleakage in the occlusal area of the cavity is not significantly different in any of the 3 groups, but The amount of microleakage in the gingival area has a significant difference so that the amount of microleakage of Futurabond NR is significantly higher than the two groups of Futurabond DC and Solo Bond M.

 chronic periodontitis is a slowgrowing inflammdory disease mostly evident in adults Many mental disorders such as depression are related to some physical diseases. This study was conducted with the aim of determining the indicators of chronic periodontitis in people with major depression compared to healthy people in Ilam city in 2021-2022.

 The type of cross-sectional study is descriptive and analytical. The statistical population included 84 patients with major depression who are hospitalized or outpatients in the psychiatric department of Mustafa Hospital. Information was collected through a researcher-made form. This form contains two parts: demographic information part (age, sex, education, place of residence, contact number, duration of illness); periodontal information section (including plaque index, pocket depth, bleeding and adhesion limit). Data were analyzed using SPSS software version 18 and t-tests, analysis of variance and Pearson's correlation.

 In this study, 84 people including depressed patients (42people) and healthy people (42people) were investigated. The average age of the two groups was 36.11 and 32.9 years, respectively. The indices of pocket depth and buccal and palatal bleeding, clinical attachment level and plaque were significantly higher in depressed patients. Older age, female sex, and lower education were more common in people with depression, but only the level of education was statistically significant (P<0.001). BOP in depressed patients was significantly more than healthy people.(p<0.01) This plaque index was significantly higher in depressed patients with less and higher education than healthy people .(p<0.01)

 It seems, Periodontal indexes such as gingival bleeding and pocket depth were higher in patients with major depressive disorder.

 Periodontal disease causes the destruction of tooth supporting tissue. Anaerobic Gram-negative bacterium, Porphyromonas gingivalis is one of the causes of this disease. Recently, due to the many side effects of mouthwashes and antibiotics, herbal materials have been receiving attention. licorice plant, with the scientific name Glycyrrhiza glabra, has antiviral, antibacterial and anti-inflammatory properties. Therefore, the purpose of this laboratory study is to investigate the antibacterial effect of different concentrations of licorice root ethanolic extract compared to doxycycline and chlorhexidine on Porphyromonas gingivalis bacteria.

 After preparing Porphyromonas gingivalis(ATCC 33277) bacteria from Isfahan University of Medical Sciences and bacterial culture and preparation of the plant and extraction, 6 dilutions of the extract were prepared. The test was carried out against Porphyromonas gingivalis bacteria along with 0.2% chlorhexidine mouthwash and doxycycline 100 mg antibiotic, with two methods of disk diffusion and microdilution. Data were analyzed by Mann-Whitney and Kruskal-Wallis statistical tests in spss26 software at a significance level of 5%.

 All six concentrations had significant antibacterial properties compared to each other and to chlorhexidine and doxycycline(P=0/001). The inhibitory concentration of extract, MIC70 and MIC90, was related to 6.25 and 200 mg/ml concentrations, respectively. The inhibitory percentages of chlorhexidine and doxycycline were 82.4% and 77.8%, respectively.

 Licorice root ethanolic extract showed a very good antimicrobial effect. So that in higher concentrations, an equal or even greater effect was obtained than the chlorhexidine and doxycycline.

  Soft tissue reactive lesions are the most common oral lesions. Eosinophils are leukocytes with multiple functions, which are considered to have multiple roles including angiogenesis and fibrogenesis. Considering the importance of reactive lesions and their prevalence in the Iranian population, this study attempts to investigate the role of eosinophils in the formation of common reactive lesions of the oral cavity.

 In this cross-sectional descriptive-analytical study, 26 case of pyogenic granuloma, 27 case of irritation fibroma and 27 case of peripheral ossifying fibroma were selected from the archive of the Oral Pathology Department of Isfahan Dental School, which were prepared by excisional biopsy method. Clinical information including age, gender and location of the lesion was extracted. Congo red staining was performed and the number of eosinophil was counted. All data was entered into SPSS24 software and was statistically analyzed by Chi-square, Fisher's exact and Mann-Whitney tests. P<0.05 was considered as a significant difference.

 The highest mean number of eosinophils was counted in pyogenic granuloma (24.88±32.08) and the lowest was counted in irritiation fibroma (10.11±23.22). According to the Kruskal-Wallis test, there was a significant difference in the average number of eosinophils (P = 0.001)

 The number of eosinophils in the studied lesions, especially pyogenic granuloma is noticeable and can play a role in the pathogenesis of these lesions.

 Ectodermal dysplasia is a genetic condition that affects ectodermal derivatives such as skin, hair, nails, teeth and sweat glands. The disease is diagnosed at birth or in early childhood. Tooth developmental disorders are observed in different forms in these children. These disorders expose children to ridicule, which can lead to psychological problems; Therefore, the physical treatment of these children is very important, especially in the oral area. This report describes the appearance and dental treatments performed on a 6-year-old girl with ectodermal dysplasia.

Case Report:

 A 6-year-old girl with no systemic disease complained of a history of being ridiculed by her peers. Lack of deciduous and permanent teeth and conical teeth were visible in this child. The child had reduced, thin hair, hypotonic lips, and a dry mouth. The bridge of the nose also seemed concaved. The baby's teeth had no caries or periodontal disease. The treatment plan for this child included a composite build-up of the conical anterior teeth and then the design of a removable partial denture to preserve the space of the missing teeth as well as their replacement.

 Removable prostheses are a suitable treatment option for children with ectodermal dysplasia. After the age of 18, surgical treatments for implant placement and then placement of implant-based prostheses can be considered.

 Odontogenic myxoma is a benign, uncommon odontogenic tumor that includes about 3 to 6% of odontogenic tumors and has an ectomesenchymal origin. It usually occurs in the second to fourth decade of life. Its common site is lower jaw and posterior parts. Treatment of lesion is complete surgical excision of tumor.

Case Report: 

The patient, a 17-year-old girl, complained of swelling of palate two months ago. In the panoramic radiograph, a single, multilocular, radiolucent lesion with relatively well demarcated borders was observed on left side of maxilla. The lesion had spread from midline to mesial of left second molar. The lesion was removed by osteoctomy. In microscopic examination, the possibility of myxoid neurofibroma was raised due to presence of wavy cells. Neurofibroma diagnosis was rejected by immunohistochemical method and odontogenic myxofibroma was diagnosed.

 In clinical and radiographic examination of this tumor, the possibility of a non-odontogenic lesion of nerve origin was raised, and in microscopic examination of excisional sample, due to the observation of wavy cells, the possibility of a myxoid neurofibroma was raised, but the IHC findings were not in favor of it. Therefore, definitive diagnosis requires relationship between clinical and radiographic findings and examination of various microscopic sections, and in case of doubt, IHC should be performed. Since odontogenic myxoma is a locally invasive lesion and has the potential for recurrence, its correct diagnosis is of great importance.