مجله تحقیق در علوم دندانپزشکی
سال نوزدهم شماره 4 (پیاپی 74، زمستان 1401)

The aim of this study was to evaluate and compare the effect of curcumin and ibuprofen on pain control, in terms of pain intensity and duration of analgesia after extraction of the third molar of the mandible in the maxillofacial surgery department of the University School of Dentistry Islamic Azad Medical Sciences in the academic year 1400-1399.

The study was performed as a double-blind randomized clinical trial on 48 patients who were candidates for mandibular third molar surgery. they should also write their pain intensity one hour after taking the second dose of the drug after seeing the first symptoms of pain based on the VAS scale and the duration of their analgesia from the time of taking the drug (which was one hour before surgery for all patients) to the first signs of pain appeared on a piece of paper. Data analysis was performed using Two sample T test power analysis of PASS software version 22.

The results of our study showed that the duration of analgesia after Curcumin use is shorter compared to Ibuprofen (P<0.001). This difference was also statistically significant. Also, after taking the second dose of the drug, patients treated with ibuprofen reported less pain intensity, although this difference was not statistically significant (P=0.39)

 Ibuprofen compared to Curcumin further reduces patients' pain and also has a longer duration of pain for patients after extraction of the third molar of the mandible.

Nowadays, demand for same–color restorative materials, especially resin composites, is increasing. Access to the smooth surface with minimum level of surface roughness significantly results in more beauty, and the reduction of the accumulation of the plaque, gingival inflammation, and tooth discoloration. the aim of this study was surface roughness of three different composite’s resins following the polish with a two-step technique has been evaluated.

In this experimental study, three types of composite; Charisma Classic, Charisma Topaz and Charisma Diamond have been investigated. Every type of the composite includes 40 disc-shape specimens with 5 and 3mm in height were provided. Specimens of each composite type were divided into two categories, tested group and negative control group. The tested groups were polished by twisted and the control groups were not subjected to any kind of polishing process. Then, the overall level of surface roughness in each group was measured. The data were analyzed with independent t test, ANOVA and the Tokay Test.

The mean surface roughness of all three types of composites after polishing by the twisted was significantly lower than the control group (p <0.001). The mean level of surface roughness in Charisma Classic and Charisma Topaz composites was not significantly different.(P=0.2) the mean surface roughness in Charisma Diamond composite was significantly higher than Charisma Classic and Charisma Topaz composites (p <0.001). The mean of surface roughness was not significantly different between the three control groups (p = 0.24).

Microhybrid composite showed the lowest level of surface roughness after the standard polishing process.

The most esthetic smile is when the entire length of the crown of the tooth and 2 mm of the gums are visable. Most of it is not aesthetically pleasing and is called gummy smile or gingival smile.Upper lip length is one of the factors influencing the gummy smile. The aim of the present study was to investigate the upper lip length in patients with vertical growth pattern, with and without gummy smile and related factors.

This cross-sectional study was performed on 180 patients referred to the dental clinic of Tehran Dental Branch of Islamic Azad University. Patients were randomly divided into three groups vertical growth pattern (VGP), Average growth pattern (AGP) and gummy smile. The length of the upper lip in all three groups was measured and compared by the caliper. T test, ANOVA and Tukey tests were used to compare the data.

In both sexes (men and women), the mean upper lip length was significantly higher in patients with vertical growth pattern without gummy smile than patients with normal growth pattern (P<0.001) and in patients with vertical growth pattern with gummy smile (P<0.001). In people with a normal growth pattern (P<0.001) and in people with a vertical growth pattern with gummy smile (P = 0.004), the mean length of the upper lip in men was significantly higher than in women. However, in people with a normal growth pattern without gummy smile, the mean length of the upper lip in men was not significantly different from that in women (P = 0.139).

Gender  vertical growth pattern, and gender interaction with vertical growth pattern  affect the upper lip length. The pattern of vertical growth affects the parameters of the smile in people with gummy smile.

With the increase of elderly population nowadays, the prevalence of denture stomatitis has increased, the etiology of which is Candida albicans .Due to the effectiveness of antifungal drugs to treat this disease. The purpose of this study was Evaluation of antifungal effect of denture adhesive after combination with three separate substances, chlorhexidine, nystatin and chamomile extract, against Candida albicans  .

This experimental study was performed on candida albicans (in vitro) in microbiology laboratory, faculty of Dentistry, Islamic Azad University of shiraz in 2019-20. The standard species of Candida albicans was inoculated in Sabord dextrose agar medium and incubated at 37 ° C. The denture adhesive was prepared according to the factory instructions and entered in standard antibiogram size molds and 50 microliters of chlorhexidine, Matrica and nystatin mouthwashes were combined with the denture adhesive, respectively. The combined materials were added to Candida albicans medium by disc diffusion and well method and the plates were incubated for 24 hours. Finally, the diameter of the stunting halo was measured in millimeters to test the research hypotheses of Kruskal-Wallis nonparametric tests (mean of several independent groups), Mann-Whitney (mean of two independent groups) and single-group mean, at the level of 0/05 significance used.

All compounds acted significantly differently compared to their raw state (P <0.05). The matrica-denture adhesive combination (10.66 mm) was better than the matrica alone (9.61mm) and nystatin(25.94mm) was more effective than the nystatin-denture adhesive(23.33mm). Chlorhexidine was also more effective than the combination with denture adhesive. Comparison of mean rank values shows that the combination of denture adhesive and nystatin is significantly more effective than other compounds and the effectiveness of chlorhexidine-denture adhesive and matrica-denture adhesive is not significantly different from each other (P> 0 / 05).

The combination of all three mouthwashes with denture adhesive has anti-candida effects, among which the combination of nystatin with denture adhesive has the strongest effect, secondarily the combination of chlorhexidine and denture adhesive, and finally the matrica composition.

Deviation from the original shape of the canal leads to poor filling and lack of proper canal seal and consequently to the failure of root treatment The aim of this experimental study was to determine the extent of apical transportation after instrumentation with hand K-Flexofile and BioRace rotary instruments by cone-beam computed tomography (CBCT).

In this experimental ex-vivo study Fifty-four extracted maxillary first molars with 19-22 mm length and 5-25 degrees of curvature were selected. The mesiobuccal canals were prepared using either the K Flexo file and Bio Race rotary files. To compare apical transportation, CBCT images were taken before and after canal preparation. The apical transportation values were analyzed using the SPSS software 18  and T-Test, Mann-Whitney ,X2.

the mean canal transportation in 1 mm from the apical foramen with Bio Race are more than K Flexo file (P = 0.000).  And the mean canal transportation in 3 mm from the apical foramen with K Flexo file are more than Bio Race (P= 0.047). The Bio Race and K Flexo file  at 2mm from the apical foramen were not significantly different in causing transportation (P= 0.899)

Root canal transportation can be seen in all techniques, regardless of the file type used. Although both rotary and manual systems in this study showed some apical transportation, But they both had the same ability to maintain the centrality and curvature of the root canal.

In respect to this fact that drug and tobacco products use is detrimental to general health and oral health, medical affiliated students could have the vital role of in prevention of this habit. This survey, aims to assess the awareness and attitude of students of Shahid Sadoughi University of medical sciences toward effects of drug and tobacco products on oral health in academic year 2019-2020.

This cross-sectional study was performed on 283 students of university of medical sciences using a self-administered questionnaire. The questionnaire composed of three parts: sociodemographic characteristics, 10 questions about awareness and 7 questions related to attitude, respectively. Data were analyzed using SPSS23 software and descriptive statistics and T-test and one-way ANOVA. The significance level was set as P < 0.05.

The mean score of awareness and attitude of students were 7.10 ± 1.07 and 23.33 ± 4.08, respectively. Score of awareness had a meaningful difference on the basis of age (P=0.01). The awareness of dental students was significantly higher rather than other students. (P=0.001).

The students' knowledge toward effects of drugs and tobacco products on oral health was in desirable level and their attitude was good.

  Panoramic radiography is routinely used in addition to clinical examination for diagnosis and treatment plan in orthodontics. The aim of this study was to determine the frequency and location of random dental and pathological findings in panoramic images before orthodontic treatment. Related  to attending of private orthodontic clinic during 2013-2018.

 In this cross-sectional descriptive study, primary panoramic images of 510 orthodontic patients who referred to a private orthodontic office in Sari during 2013-2018 were used.  Panoramic images were examined independently by two observers after stabilization in light conditions and standard magnification on a monochromatic screen.    Data were analyzed using Chi-square test.

 Panoramic images of 510 patients (274 images of female patients and 236 images of male patients) with a mean age of 32.3 years were used in this study. The frequency of tooth and root abnormalities was 26.65%, with the highest finding related to impacted teeth (19.6%) and the lowest related to root dilaceration (0.39%).The frequency of pathological lesions was determined to be 9.42%, the most common of which was associated with apical pulp lesion (4.71%) and the rarest bone sclerosis (0.39%). There was no significant difference between the two sexes and between the two jaws in terms of the frequency of pathological lesions and root dental abnormalities except impacted teeth. The frequency of impacted teeth in female (P value = 0.002) and in maxilla (0.007) P value =) was significantly higher.

 Clinicians should always be aware of the potential for pathological findings and dental abnormalities in patients' primary panoramic images, which is a valuable radiograph to detect abnormalities.

  Panoramic radiography is routinely used in addition to clinical examination for diagnosis and treatment plan in orthodontics. The aim of this study was to determine the frequency and location of random dental and pathological findings in panoramic images before orthodontic treatment. Related  to attending of private orthodontic clinic during 2013-2018.

In this cross-sectional descriptive study, primary panoramic images of 510 orthodontic patients who referred to a private orthodontic office in Sari during 2013-2018 were used.  Panoramic images were examined independently by two observers after stabilization in light conditions and standard magnification on a monochromatic screen.    Data were analyzed using Chi-square test.

Panoramic images of 510 patients (274 images of female patients and 236 images of male patients) with a mean age of 32.3 years were used in this study. The frequency of tooth and root abnormalities was 26.65%, with the highest finding related to impacted teeth (19.6%) and the lowest related to root dilaceration (0.39%).The frequency of pathological lesions was determined to be 9.42%, the most common of which was associated with apical pulp lesion (4.71%) and the rarest bone sclerosis (0.39%). There was no significant difference between the two sexes and between the two jaws in terms of the frequency of pathological lesions and root dental abnormalities except impacted teeth. The frequency of impacted teeth in female (P value = 0.002) and in maxilla (0.007) P value =) was significantly higher.

Clinicians should always be aware of the potential for pathological findings and dental abnormalities in patients' primary panoramic images, which is a valuable radiograph to detect abnormalities.

Delayed detection of SARS-CoV-2 has been a major hindrance in curbing the current COVID-19 pandemic. Wide spread testing is the most practical way out of the current crisis. The current gold standard for COVID-19 diagnosis is real-time reverse transcription polymerase chain reaction (RT-PCR) detection of SARS-CoV-2 from nasopharyngeal swabs. However, collecting nasopharyngeal swabs causes discomfort to patients due to the procedure’s invasiveness, limiting compliance for repeat testing, and the procedure presents a considerable risk to healthcare workers. Therefore, developing rapid and convenient ways of testing for COVID-19 will greatly enhance the capacity of testing. Alternatively, saliva is a promising candidate for SARS-CoV-2 diagnostics. The purpose of this review is to provide an update and review of the composition of the latest research and to compare the various methods and techniques developed for the diagnosis of COVID-19 by saliva.

In this review article, data were collected by searching articles which were published between year 2019 and 2021 in domestic and foreign journals, using databases such as: PubMed, PubMed Central, Medline, EBSCO, Google Scholar and Embase with keywords: Saliva, Covid_19, Covid_19 Test, Salivary Test. Among the relevant authorities, the articles that were cited many times and were more up to date, were selected.

that saliva is an acceptable alternative source for detecting SARS-CoV-2.  It imposes the development ofnew strategies for COVID-19 diagnosis; however, despite the colossal demand for novel diagnostic platforms with non-invasive and self-collection samples of COVID-19, the accuracy of salivary SARS-CoV-2 platforms are still not well- elucidated.

Central Ossifying Fibroma is a benign bone neoplasm. It has been categorized under fibro-osseous lesions and has significant growth potential that exact etiology is not known. According to studies it has a periodontal ligament origin. It is more prevalent in women and mandibular premolar and molar area. The lesion generally occurs in the third and fourth decades of life. Tumor removal by surgery or curettage are suitable treatment and its recurrence rate is reported to be between 0 to 28%. Most of the time the prognosis of the lesion is optimal nevertheless in some cases, malignant transformation has been reported.

Case Report:

 A 25-year-old woman was referred for dental treatment. The CBCT view demonstrated an ill-defined radiolucent-radiopaque lesion in right mandibular body, lack of lamina dura of the lower right canine tooth and destruction of the buccal and lingual cortex of that area. The lesion was removed by osteoctomy. In microscopic view, the histopathological profile of central ossifying fibroma was observed without evidence of malignant changes. Follow up of the patient after 6 months indicated complete healing and bone formation at that site.

It seems, ossifying fibroma can havd ivvassive feature in radio graphy and mimic malignant lesions. So, microscopic evaluate of all sections is important.