e. hosseini

The emotional expression of feelings and the satisfaction of social needs are two primary purposes of many communication interactions in an organization. As a universal aspect of human interaction, the apology has sparked great interest in its study across a wide range of disciplines. However, the human resources apology has not been involved integrally in the context of organizational communication. Therefore, the research question is, what are the dynamics of human resources apology in organizational communication in Iran? This was a qualitative study conducted using grounded theory. The research was conducted, and sampling was theoretical in municipalities in Iran. For data collection, semi-structured in-depth interviews with the 5W1H technique were conducted with 13 managers, who respond to citizens’ requests in the central building of municipalities in Iranian provinces. The researched community comprises human resource managers with at least five years of beneficial work experience in the municipality and relevant knowledge of apology. Targeted sampling has been done based on the researcher’s considerations.                                                          The analysis of the interviews resulted in a set of fundamental topics collected during the open coding process. Sixteen categories were extracted from these fundamental topics. Then, in the axial coding stage, the link between these categories was determined under the following headings causal conditions, core category, contextual conditions, intervening conditions, strategies, and consequences of human resources apology in the form of an axial coding paradigm. In the present study, data analysis was performed using ATLAS. ti software version 8 in three stages of primary, central, and selective coding, which resulted in the identification of 5 categories, 15 central concepts, and 126 final codes. The developed process model provides a comprehensive understanding of the human resources apology process in municipalities in Iran. The study highlights the importance of conflict management, individual behavior, motivation, audience strength, acceptability, apology graph, apology method, audience identity, communication quality, patience, and incompatibility in the human resources apology process.

The collection and storage of platelets is associated with several challenges, to prevent the activation of platelets on the one hand and maintain their functional capacity during blood transfusion on the other hand. Today, one of the problems of platelet concentrate is the existence of platelet aggregations. The suspended particles in the platelet concentrate are believed to contain platelets that accumulate during the preparation and separation. The purpose of this study was to review important variables in the formation of platelet aggregations.

In this review article, 47 articles about aggregates in platelet products were studied from the PubMed database with platelet concentrate and platelet aggregate keywords.

In the reviewed studies, the accumulation of platelets in the platelet concentrates prepared by the Platelet-rich plasma (PRP) method was higher than in the buffy coat and apheresis methods. Various factors such as storage temperature, time and temperature of platelet rest, pH, induced physical stimulation, type of platelet bag, presence of bacteria, and variables related to the donor were considered as factors involved in the formation of platelet aggregation.

Conclusions  :

It is necessary to know the important variables in the formation of platelet aggregations to improve the platelet product's quality and increase the platelet transfusion's effectiveness. Using the Buffy coat method, standardizing time and temperature, preventing bacterial contamination, and considering the variables related to the donor are some of the proposed solutions to reduce the possibility of platelet aggregation.

In the 80s, cord blood stem cells were used for the first time to treat diseases in humans, and contrary to the opinion of the opponents of using this new cell source, the result was satisfactory, and since then, cord blood has been an important source for cell therapy in humans. Considering the dominant approach to increase the clinical use of umbilical cord blood and the expansion of experimental and research studies in this field, this review article has discussed the current applications and future perspectives while examining the biology of cord blood stem cells.

To conduct this review, the key words “cell bank, umbilical cord blood, Wharton's jelly, stem cell and mesenchymal stem cell” were searched in PubMed and Google scholar databases in the period from 1990 to 2022.

Cord blood cells have significant biological differences compared to other sources (bone marrow and peripheral blood).The absolute number of lymphocytes in cord blood is higher than the peripheral blood and the relative number of natural killer cells in cord blood is higher. Also, cells derived from umbilical cord blood have longer telomeres and more self-renewal capacity than peripheral blood and bone marrow, which makes them very potent.

Conclusions :

This source is of interest not only because of its high immunomodulatory properties in the treatment of inflammatory, autoimmune and systemic diseases, but also because of its anti-inflammatory properties, high differentiation ability and high proliferation capacity, as an ideal option for cell therapy in diseases in addition to hematological disorders. In addition, the preparation, processing, maintenance and storage of cells derived from umbilical cord blood are easy and inexpensive, which is an important point for treatment systems worldwide.

The employee's experience during employment can play a very important role in various aspects of the employee-employer relationship and subsequently in the personal improvement of the employee and the development and progress of the organization. Due to the fact that so far, the experience of employees has not been measured with regard to the effect of job satisfaction, workplace and organizational culture, this research has innovation. Therefore, the purpose of this research is the identifying the dimensions of employee experience according to the effect of satisfaction, workplace, and organizational culture.

This study is applied and descriptive. The statistical population consisted of employees of the municipality of Kohgiluyeh and Boyer Ahmed provinces. The statistical population of the research included 823 municipal employees, which was estimated to be 260 for the statistical sample according to the online Cochran formula. The researcher-made questionnaire was compiled according to the research literature and sent to the statistical sample through the porsline link of the questionnaire.  For content validity, the evaluation of scientific and executive experts who are aware of the subject and society showed that the questions of the questionnaire evaluate the variables and their relationships well. In the measurement model, the internal consistency of the model or reliability has been measured by calculating Cronbach's alpha coefficient and shared reliability. To measure divergent validity, Fornell and Larcker criteria were used. Data analysis was done using the software of structural equations of Lisrel.

Convergent validity and Cronbach's alpha were used to fit the measurement. The convergent validity was higher than the standard value of 0.5, which was acceptable for all variables. Cronbach's alpha was higher than the standard value of 0.7, which was acceptable for all variables. The t-statistic was used to test the hypotheses. The amount of t-statistic for culture and satisfaction variable was more than the acceptable limit, i.e. 1.96, which means that these two hypotheses have been confirmed. The value of t statistic was less than acceptable and this hypothesis was rejected.

Considering the relationship between organizational culture and job satisfaction with employee experience, there is a need for managers to try to carry out activities or make decisions that increase employee job satisfaction and improve and make organizational culture more effective in order to create an effective experience and be efficient for employees.

Among the important factors affecting female infertility, endometriosis (with a prevalence rate of up to 50% in infertile women) has a special place. Endometriosis, which is known as the presence of endometrial glands and stroma outside the uterine tissue, causes a wide range of functional disorders in the process of follicular development and changes in the follicular microenvironment, which ultimately leads to the creation of an egg that is of suitable quality for the formation of The fetus does not have Therefore, the aim of the present study was to determine and investigate post-translational changes of histones, DNA methylation level and ERβ protein level in the genome of cumulus cells of infertile women with endometriosis.

The present case-control study was conducted at the infertility treatment clinic of Royan Research Institute in 2014. Twenty-four patients were divided into two equal groups. Cumulus cells were obtained from 12 infertile patients with endometriosis and 12 women with male factor infertility (as a control group) under ovulation stimulation protocols for intracytoplasmic sperm injection. Extraction of chromatin from cumulus cells was done after stabilization of DNA binding proteins and then cell lysis and preparation of soluble chromatin. The binding and incorporation levels of MeCP2 protein (as DNA methylation marker), two epigenetic markers related to histone modifications (H3K9me2 and H3K9ac), and ERβ protein to chromatin of cumulus cells were evaluated using the corresponding primary antibodies, secondary antibodies conjugated and Nucleosome-ELISA technique. Data were analyzed using independent t-test t and Levene's test.

MeCP2 protein incorporation into DNA was significantly higher in the endometriosis group than in the control group. The level of two epigenetic marks H3K9ac and H3K9me2 in the chromatin of cumulus cells of the patient group showed a significant increase compared to the control group (P<0.05). In addition, an increased level of binding of ERβ protein to the genome was observed compared to the control group.

Epigenetic changes, including histone hyperacetylation and hypermethylation, and DNA hypermethylation of the whole genome of cumulus cells of patients with endometriosis had occurred, accompanied by an increase in the level of ERβ protein binding.

The influence of smartphones in face-to-face interactions has presently affected the methods of human interaction in various social environments and has led to the emerging phenomenon of phubbing.  Phubbing has been the focus of researchers as the employee's perception that his/her supervisor is distracted by their smartphone while talking or being in close proximity to each other in the work environment. Therefore, it can be stated that phubbing is negatively related to subordinates' trust in their supervisor. So. the present study aimed to identify the antecedents and consequences of phubbing in Yazd municipality. The present study was applied in terms of purpose and qualitative in terms of research methodology and based on the grounded theory approach. We decided to apply this method because the core objective is to choose the individuals who are acquainted with such phenomena. Consequently, it will be easier to comprehend the topic so that the samples can provide appropriate answers accordingly. In the present study, for performing data collection, semi-structured in-depth interviews with the 5w1h technique were conducted with 12 people, including managers and employees who respond to citizens’ requests in the central building of Yazd Municipality. The researched community consists of The Experts selected were those who had relevant articles, at least three years of beneficial work experience in Yazd Municipality, and relevant knowledge of phubbing. Targeted sampling has been done based on the researcher's considerations. The present study was performed March 2023. The findings show that there are many empirical factors influencing phubbing in organizations, so that the role of employees and their functional duties are considered a very influential factor for phubbing in organizations. Employees should be able to have a detailed understanding of their needs and their behavior in the organization in interactions so that they can convey the best experience to them in order to influence their behavior. If the set of municipality facilities can perform their duties well, a positive experience can be created in the employee's mind. Therefore, human resources, physical space and functional aspect will provide a very effective role in creating a positive experience and provide a suitable mental background for employee preferences. In the present study, data analysis was performed using Maxqda software version 20 in three stages of primary, central, and selective coding, which resulted in the identification of 6 categories, 21 central concepts, and 123 final codes. Therefore, technological factors, social factors, personal/individual factors, cultural factors, and psychological factors were identified in this research. The results of the data analysis indicated that there were many experimental factors influencing phubbing in organizations so the role of employees and their functional responsibility were considered to be a highly influential factor for phubbing in the municipality. The interviewees believed that employees must quickly feel secure and comfortable after becoming a member of the organization and they must adapt themselves to the norms of the environment. Therefore, considering that fobbing has attracted the attention of many researchers, as far as the authors are aware, its antecedents and consequences have not been identified, from this point of view, the research has innovation.

Gamma irradiation (GI) to platelet products is a usual therapeutic procedure for preventing the transfusion associated graft versus host disease (TA-GVHD) in susceptible recipients. Nevertheless, some studies indicate a decrease in platelet recovery after transfusion, associated with higher levels of platelet storage lesion (PSL) in gamma irradiated platelets. In addition, the induction of oxidant stress, especially the increase in the production of reactive oxygen species (ROS) following the treatment of platelet products with gamma rays, has been reported in some studies. Therefore, given the known effects of ROS on PSL induction, the review presented here, while introducing different sources of ROS production during storage, also discusses the importance of storage-dependent oxidative stress in platelet products exposed to gamma radiation. For this purpose, studies published in MEDLINE, PubMed and Google scholar were searched for relevant keywords, among which 66 studies were cited in this review.

Interleukin-10 is an important immunoregulatory cytokine that has an inhibitory effect on the initiation and progression of inflammatory responses in different situations such as autoimmune diseases including rheumatoid arthritis. Polymorphism in IL-10 promoter region affects the expression of this gene. It therefore seems reasonable that these polymorphisms may contribute to rheumatoid arthritis susceptibility in special populations. the aim of this study was to investigate the association between IL-10 rs1800872 polymorphism in the promoter region of human IL-10 gene and susceptibility to rheumatoid arthritis in the patients in southwest of Iran.

The present study is a case-control study conducted among patients with and without rheumatoid arthritis referred to the Mofateh clinic in Yasuj, Iran. Both case (n=64) and control (n=65) groups were selected using purposive sampling and were matched in terms of age, gender and ethnicity. Peripheral blood samples were collected from subjects and rs1800872 genotypes were determined by polymerase chain reaction-restriction fragment length polymorphism method. SPSS 26.0 software was used for statistical analysis of data

The association between the frequency of TT genotypes and the incidence of rheumatoid arthritis was significant (OR=6.45; 95% CI= 1.30-32.00; p=0.023). On the other hand, the distribution of the T allele showed a significant relationship with rheumatoid arthritis (OR= 2.23; 95% CI= 1.26–3.97; p=0.006).

TT genotype of rs1800872 polymorphism is associated with rheumatoid arthritis susceptibility in southwestern Iranian population and can be considered as a risk factor for rheumatism.

Two spotted mite, Tetranychus urticae Koch. is one of the most important plant pests. Chemical pesticides are used to control this pest, which increases pesticides residual, eliminates natural enemies and contaminates groundwater. In this regard, the effect of diatomaceous earth, silica nanoparticles, kaolin and micronized sulfur and their mixing on different biological stages of two spotted mite were evaluated in laboratory condition. The results of probit analysis showed that the LC50 of nano silica was equal to 180.00 mg/L after five days for egg stge. For third nymphal and adult stages the LC50 were 30.51 and 43.01 after 72 hours respectivly. In studying the effect of mixing the compounds, the highest lethal effect against eggs, 3rd nymphal stage and adult mites was obtained by mixing sulfur and nanosilica. Comparison of the average effect of diatomaceous earth, nanosilica, kaolin, sulfur treatments and their combination on leaf chlorophyll index showed that the highest index was in sulfur treatment (42.53). Also, the least oviposation and production of offspring was observed in mixing of sulfur with nanosilica. Due to the significant effect of sulfur and nanosilica mixing, thus, it can be used in integrated pest management program against eggs, 3rd nymphal stage and adult of this pest.

During storage, platelets may lose their functional capability and structural integrity. This process is often called as "platelet storage lesion" (PSL), which is characterized with changes in morphology, metabolism, membrane structure, and expression of platelet activation and apoptotic markers. Apoptosis, or programmed cell death, is an energy-dependent physiological mechanism that results in the controlled removal of unwanted or damaged cells. While it has long been attributed exclusively to nucleated cells, many studies demonstrated that apoptosis also occurs in anucleate cells and platelets.

Studies published in MEDLINE, PubMed, and Google scholar are assessed for keywords and 55 articles is cited

The present review article describes the different apoptosis pathways in platelets, while adressing the markers, methods and probes used for evaluating apoptosis in platelet concentrates.

The evaluation of apoptosis can play an important role in identifying the mechanisms involved in platelet storage lesion.

Entrepreneurship has become mandatory for different societies because not only does entrepreneurship make it possible for individuals to access the financial resources generated by the idea but it also facilitates the development of a country by solving problems in a new way. Accordingly, the purpose of this study is to explore and determine the relationship between entrepreneurial skills on job performance of managers and deputies working in the municipalities of Hormozgan province located in the south of Iran.

The present study is a descriptive-practical correlation in terms of how data was collected. The collected data were based on the quantitative research method used to measure job performance by means of the Standard 15 Questionnaire. For evaluating the entrepreneurship skills, the 20 researcher-made questionnaire with 20 statements was used based on the research literature. The statistical population of the study consisted of 350 managers and deputy mayors of Hormozgan province. By applying the Cochran's formula, 182 people were selected as the statistical sample. Data analysis was performed by means of SmartPLS3 software.

The results of the research indicate positive relationships among entrepreneurial (3.695), managerial (5.680) and technical (7.369) skills concerning job performance. Therefore, these hypotheses were confirmed and, on the contrary, the hypothesis related to the relationship between personal skills and job performance (1.774) was rejected.

According to the findings, the development of the relationship between entrepreneurial skills on job performance of managers and deputy mayors of Hormozgan province improves the competitive performance of organizations.

Metabolic syndrome is the result of a general imbalance of metabolic processes in the body which increases mortality due to cardiovascular disease. The syndrome has recently attracted the attention of health care researchers to its impact on quality of life. Rational differences and occupational diversity affect the prevalence of metabolic syndrome. The purpose of this study was to determine the prevalence of the disease among Gachsaran oil industry employees. The present paper was a descriptive cross-sectional study. During the years 2016-20173, 360 employees were randomly selected using a questionnaire, Alpikado pressure gauge, and Scala scale. Fasting blood samples were taken to measure triglyceride, glucose, LDL, HDL, and total cholesterol. Diagnosis was performed using NCEP ATP III criteria, with prevalence of less than 10, 10-25 and above 25% as low, moderate and high prevalence respectively. The collected data were analyzed using Chi-Square and logistic regression. The prevalence of metabolic syndrome in the whole sample was 30.3, 31.2 and 7.1%, respectively. Furthermore, the prevalence of abdominal obesity was 74.1%, thyroid triglyceride 46.6%, high systolic blood pressure 39, HDL cholesterol Low 33, fasting blood glucose was 13.3 and high diastolic pressure was 13%. A reduction in serum HDL cholesterol and one increase in waist circumference, systolic blood pressure, fasting blood glucose and triglyceride were associated with a 15, 14, 7, 4 and 1 percent increase the odds of contracting a disease , respectively. The prevalence of high metabolic syndrome was higher; in addition, the prevalence was higher in men than in women. This indicated the impact of gender differences and occupational situations on the prevalence of this metabolic disorder. Therefore, the necessity of paying more attention to specific occupations in periodic studies is recommended.

Ginger is widely used by pregnant women and nursing mothers as a remedy for nausea and vomiting. This study aimed to investigate the effects of the alcoholic extract of ginger on serum levels of estrogen, progesterone, follicle-stimulating hormone (FSH), luteinizing hormone (LH) and ovarian follicles during pregnancy and lactation in the adult, female offspring of rats. This experimental study was conducted on 72 adult female rats, which were divided into 9 groups of 8, including the control groups, and recipients of 200, 100, 50 mg/kg of ginger alcoholic extract (perinatal and neonatal). Drug administration was performed via oral gavage, and by the end of infancy, the female offspring of each group were separated. At puberty, 8 animals were randomly selected from each group, and after blood sampling, serum levels of estrogen, progesterone, FSH and LH were measured. In addition, the number of follicles and yellow bodies (corpus luteum) were determined after the removal of ovaries. In comparison with the control groups, ginger caused a significant increase in the levels of estrogen (93.36±5.78), progesterone (4.52±0.45), FSH (0.90±0.05) and LH (0.79±0.08) in the experimental groups. Moreover, there was a significant increase in the number of follicles (6.40±0.33) and yellow bodies (7.00±1.41) in all the experimental groups (p≤0.05). According to the results of this study, consumption of ginger during pregnancy and lactation could increase the serum levels of estrogen, progesterone, FSH and LH, as well as the number of ovarian follicles, in the female offspring of rats.

the method for measuring the congestion of Noura et al. [A.A. Noura, F. ‎Hosseinzadeh Lotfi, G.R. Jahanshahloo, S. ‎Fanati Rashidi, R.P. Barnett, A new method for measuring congestion in data envelopment analysis, Socio-Economic Planning Sciences, 44 (2010) 240-246] ,there is no problem for congestion detection In the case of one input and one output but in higher space is not able to detect congestion of some units. we offer modification of the method of measuring the congestion of Noura et al. The proposed method ability congestion units go up and this method detect all congestion units.

Consumption of foods with low glycemic index (G.I.) by diabetic patients helps maintain their blood sugar at acceptable levels. Ordinary jam has a high G.I. The purpose of the present investigation was to prepare a dietetic jam using nutritive and non-nutritive sweeteners. The investigation was carried out in four steps. First, glycyrrhizin was extracted from licorice extract powder, its ammonium form was prepared, and its purity was assay by HPLC. Secondly, based on a completely randomized design various types of jam were prepared using different combinations of sorbitol, fructose and ammonium glycyrrhizin. Thirdly, the prepared jams and their reference controls were evaluated for color, flavor, texture and overall acceptability by a selected taste-panel and were also subjected to physical analysis using Hunter Lab colorimeter and Bostwick consistometer. Two jam preparations were finally selected on the basis of their overall acceptability. Finally, glycemic indices of the selected jams were determined using NIDDM volunteers. The results showed that ammonium-glycyrrhizin enhances the overall acceptability of the selected product (P<0.05). As G.I. values for the selected jams were low (23.5 and 23.9), their consumption by diabetic patients and their production on a commercial scale are recommended.