جستجوی مقالات مرتبط با کلیدواژه « green coffee » در نشریات گروه « پزشکی »

Obesity and being overweight is one of the major public health challenges all around the world. The prevalence of being overweight has been increasing over the past decade and it is estimated that more than 2 million people are overweight now. Obesity is associated with an increased risk of some chronic diseases like diabetes, cardiovascular diseases, and cancers. Several different approaches like exercise training have already been introduced to combat obesity and overweight. According to previous studies, comprehensive approaches including training exercises, dietary supplements, and medications could provide the best outcome. Metabolic resistance training has been shown as a promising approach to weight loss with higher efficacy compared with other types of exercise training. Moreover, such effects have also been reported for Chlorogenic Acid (CGA). In the current study, we aimed to compare the simultaneous effects of 8 weeks of MRT and CGA on weight loss and lipid profile of overweight women.

We performed an open-label randomized clinical trial on 40 women with overweight. Study participants were women with body mass index (BMI) between 25 to 28 who were physically active over the past 6 months before the study. We used a balanced block randomization method for case assignment. The study participants were randomly assigned to either the intervention group or a control group. The intervention given to the study participants was a combination of MRT and CGA supplements. Each MRT training session was 45 minutes including 10 minutes of warm-up, 30 minutes of MRT, and 5 minutes of cool-down. They also received CGA supplements as a form of green coffee extract (400 mg per day). We collected data on age, weight, height, BMI, medical history, and volume of physical activity for each participant. Data on lipid profiles including HDL, LDL, total cholesterol, and triglyceride were also collected for each participant at baseline using blood samples. Study participants were asked not to have vigorous exercise two in the last two days leading to blood sampling. Blood sampling was performed from the participant’s right-hand vein at 8 AM and all study participants were fasting in the last 12 hours. The same procedures were also repeated after 8 weeks of intervention.We provided and mean and standard deviation for each continuous variable. The mean comparison between intervention and control groups was performed using an independent t-test. Withing group variability of lipid profile was investigated using paired t-test. We also used a multiple linear regression model to assess the effect of CGA+MRT intervention on the lipid profile of overweight women adjusted for possible confounders. All statistical analysis was performed using Stata 17.0 software and P-values <0.05 were considered significant.  

We compared baseline characteristics and observed no statistically significant difference between the intervention and control groups regarding age, weight, and BMI. Lipid profile at baseline was also compared between these groups and there was no statistically significant difference (P >0.05). The average BMI change in the control group was 0.4 kg/m2, while it was 0.7 kg/m2 in the intervention group. We also observed a significant decrease in HDL, TC, and TG in the intervention group over the study period (P <0.05). However, no significant change was observed in the control groups regarding the investigated outcomes (P >0.05). The linear regression model showed that after adjustment for the potential confounders the average BMI reduction in the control group was 0.6 kg/m2 higher in the intervention group than the control group and the observed association was statistically significant (P <0.05). We also observed that MRT and CGA intervention has led to more reduction in HDL level on average (Regression coefficient= -8.9, 95% CI= -10.9, -7.0). The effect of the intervention on TG and TC was also statistically significant and the intervention significantly reduced the level of TG and TC in comparison to the control group (P <0.05).

The present study was conducted to investigate the effect of eight weeks of metabolic resistance training and CGA supplement extracted from coffee beans on the body weight and lipid profile of overweight women. We showed that MRT and CGA supplementation could lead reduce body weight and body mass index in the intervention group. The observed difference compared to the control group was also statistically significant. We also observed a significant effect of the intervention on the level of HDL, TG, and TC. According to our data level of HDL, TG, and TC in the intervention group reduced over the study period and the observed difference was statistically significant compared to the control group.We showed that simultaneous CGA and MRT could reduce body weight and body mass index in overweight women. Such findings were supported by many previous researches. Haghighi et al. showed in a study that participating in eight weeks of aerobic exercise and consuming green tea supplements significantly reduced body weight and body mass index. These findings were similarly repeated in the study of Kanha et al. and they showed that consuming CGA for eight weeks leads to weight loss in mice with a high-fat diet and also improves lipolysis pathways. In a systematic review study by Gerji et al., it was shown that the consumption of CGA supplements and coffee extract can lead to weight loss in overweight and obese people. According to previous studies, participating in MRT courses could effectively increase energy consumption and consequently increase fat burning which leads to weight loss. We also observed that MRT and CGA modified the lipid profile of overweight women. According to our findings, women in the intervention group had a lower level of HDL, TG, and TC after 8 weeks of MRT training and CGA supplementation. Their results were consistent with previous studies. Ghasemi et al, in line with the findings of the present study, showed that participating in metabolic resistance exercises with CGA supplementation leads to positive regulation of the lipid profile of overweight people. Animal studies also showed that MRT training and CGA supplementation could significantly reduce the level of TG, TC, and HDL in rats. Several mechanisms including the effect of CGA on LDL receptors and inhibition of mass absorption were introduced to justify these findings. According to our findings, MRT and CGA supplementation could lead to weight loss and reduced BMI in overweight women with a significant positive change in their lipid profile.

The purpose of this research was to investigate the effect of eight weeks of waterexercise and the consumption of herbal tea on body composition and quality of life in overweight and obese women.

In this experimental study, 48 obese and overweight adult women with an average body mass index of 31.16 were selected and randomly divided into 4 groups: herbal tea (n=13), water exercise (n=12), herbal tea, and exercise in water (n=12) and control (n=11). Herbal tea was consumed twice a day after lunch and dinner for eight weeks. Water exercises were performed for eight weeks, three sessions a week, and each session lasted 60 min. Body composition was measured using a body composition instrument, and quality of life was measured through a questionnaire before and after the study. ANOVA and Bonferroni post hoc tests were used for data analysis.

The results showed that the weight and BMI of overweight and obese women decreased in the   water exercise group and the group of water exercise group with tea consumption after eight weeks (P<0.05). Chest circumference, abdominal circumference, percentage of body fat, and visceral fat decreased in the water exercise group along with the consumption of tea (P<0.05). In addition, the quality of life (physical health and total score) improved in both exercise groups (P<0.01).

The results show the beneficial effect of water exercise on the body composition and quality of life of overweight and obese women. The consumption of herbal tea only had no effect.

The purpose of this research was to compare the effects of aerobic exercises and green coffee consumption as a supplement on serum meteorin-like, myonectin level, and insulin resistance in obese women in Isfahan, Iran.

A clinical trial was performed in 40 women who were randomly divided into four groups, including aerobic exercises (5 sessions per week/30-45 min/ 8 weeks), green coffee supplement (400 mg/daily), aerobic exercises (5 sessions per week/30-45 min/ 8 weeks) and green coffee supplement (400 mg/ 8 weeks), and control groups. Forty eight hr after the last exercise session, blood samples were collected (after a 12-hr overnight fast) to measure the serum meteorin-like, myonectin, insulin, and glucose levels. Data analysis was done applying dependent t-test and ANOVA.

The participants’ mean weight, height, and BMI were 81.71±6.79 kg, 161.01±6.72 cm, and 32.4±4.6, respectively. ANOVA test showed significant differences in serum levels of myonectin
(P=0.001), meteorin-like (P= 0.007), insulin (P = 0.005), fasting glucose (P= 0.001) and insulin resistance (P=0.001) between the groups studied. Aerobic exercises and green coffee intake significantly increased serum myonectin and meteorin-like levels, compared to aerobic exercises (P= 0.001) and green coffee consumption alone (P= 0.001).

Green coffee intake and periodic exercises can affect some glycemic indices. Current study confirms the role of serum meteorin-like and myonectin level in preventing obesity and insulin resistance.

This study aimed to determine the effect of 8 weeks of resistance training using elastic bands and green coffee supplement on hepatic steatosis index in obese middle-aged Women.

In this randomized clinical trial, 60 obese (33.58±2.96) and middle-aged women (42.99±3.08) were selected as the subjects and were randomly divided into four groups of 15 people: supplement, exercise+supplement, exercise+placebo and placebo. The training groups received eight-week elastic band resistance training program at 3 sessions per week and 60 minutes each session. Daily supplementary groups received a 400 mg capsule of green coffee extract. Blood samples were measured 24 hours before the start and 48 hours after the end of the protocol in the fasting state. In order to compare intra-group and extra-group, the t-test and the two-way ANOVA and post-hoc Bonferroni test were used.

The results showed that 8 weeks of exercise with supplementation, despite significantly reducing the serum levels of liver enzymes in the experimental groups, there had no significant difference with the control group. Also, 8 weeks of resistance training combined with green coffee supplementation made a significant difference in the index of hepatic steatosis in obese women.

However training with elastic bands and green coffee consumption improved hepatic steatosis index but considering that its effect on liver enzymes was not significant. it seems, improvement in liver function indices in obese women may require longer periods of resistance training and green coffee supplementation.

Exercise training along with the use of herbs is the most effective methods for improving liver function in obese people. The purpose of this study was to investigate the effect of 8 weeks of circuit resistance elastic band training with green coffee supplement on fatty liver function indices (fatty liver index (FLI) and lipid accumulation product (LAP) in middle-aged obese women.

In this randomized clinical trial, 60 obese women (33.58±2.96) and middle aged (42.99 ± 3.08) were selected as subjects and randomly divided into four supplement (15), exercise + supplement (15), exercise+placebo (15) and placebo (15) groups. The training groups received 8 weeks of circuit resistance elastic band training at 3 sessions per week and 60 minutes each session. Also, supplement groups received a daily 400 mg capsule of green coffee extract. Blood samples were taken 24 hours before the first session and 48 hours after the last training session after 12 hours. The t-test was used to compare the intra-group and the two-way ANOVA and post-hoc bonferroni test were used for comparison between groups.

There was a significant difference between the groups after 8 weeks of intervention in the FLI index (P = 0.025) and the non-significant difference in LAP (P=0.288) between the 4 groups. The results of the bonferroni post-hoc test for FLI showed a significant reduction in this indicator in the exercise + placebo group compared to placebo group (P = 0.008).

The results of the present study show that green coffee does not have a possible potential to improve liver function indices. In general, improvement in liver function indices in obese women may require longer periods of resistance training and supplementation of green coffee.

Obesity and overweight are widely expending in worldwide and containing a wide range of diseases, such as glucose homeostasis disorders. Green coffee and exercise are as suitable treatment options for this condition.

The aim was to evaluate the simultaneous effects of green coffee consumption and combine training on body composition and glucose homeostasis in overweight and obese women.

26 overweight and obese women were randomly divided into three green coffee (n=9), combined training (n=10) and green coffee - combined training (n=7) groups. Green coffee powder was consumed daily as two 125 mg per day before lunch and dinner. Combine training was contain of six weeks, four session per week of progressive endurance- strength training. Insulin, fast blood suger and HOMA and body composition factors were measured before and after the end of interventions. 

Weight, body mass index (BMI), waist circumference, hip circumference, waist to hip ratio (WHR), fat percent, insulin and HOMA levels were significantly decrease in all three groups that the reduction for all variables except waist circumference, WHR, insulin and HOMA were higher in green coffee- combine training group than two other groups (P<0.05). Blood glucose changes was not significant in any groups (P>0.05).

Results indicated that maybe both green coffee and combine training are effective for improve body composition,  insulin and HOMA levels and simultaneous usage of green coffee combine with combine training have synergistic effects on improving body composition.

Obesity is a major problem in many societies, especially women. The purpose of this study was to investigate the effect of eight weeks of aerobic exercise with green coffee consumption on the levels of follistatin and myostatin in overweight women.

In this semi-experimental single blind Clinical Trial study, 30 overweight women were randomly divided into two groups (n=15), aerobic exercise (8-Weeks, 3days/Week, 20 min/day, at the last week 60 min/day)  with green coffee and with placebo (daily). Blood samples were collected in the fasting morning before exercise and 48 hours after the last training session. After centrifugation, the samples were isolated, then for determine of gene expression, used the RT-PCR method and for the concentration of follistatin and myostatin based on ng/ml used ELISA method. Data were analysed by ANCOVA test and SPSS-22 software (p <0.05).

 Aerobic exercise combined with green coffee consumption significantly increase in follistatin expression (P= 0.004, F= 10.995) and a significant reduction in fat percentage in the both groups (P= 0.004, F= 9.809). There was no significant difference between the two groups on follistatin (P= 0.567, F= 0.34), but on the fat percentage, the difference between the two groups was significant (P= 0.0001, F=29.156). But there was no significant effect on myostatin and muscle mass in any group (P= 0.291, F= 1.182 and P= 0.745, F= 0.108).

 The combination of aerobic exercise with green coffee can play an important role in weight loss and chronic diseases associated with obesity.

 Obesity is an excessive amount of energy stored in a form of fat in body, which is a serious medical, social, and economic problem. The factors affecting obesity include geographic location, environment, genetic effects, energy imbalance, inappropriate diet, and physical inactivity. It has been shown that green coffee extract can affect weight by changing plasma adiponectin levels, distributing body fat, and decreasing the concentration of fatty acids. This study aimed to summarize the data from clinical and laboratory trials related to the effect of green coffee supplementation on weight and parameters associated with obesity.  To conduct the study, the articles published between 1990 and 2018 related to the effect of green coffee supplement on weight loss were searched in PubMed, Scopus, ISI, and Google Scholar databases. The search process was accomplished using the keywords of Green Coffee, Green Coffee Extract, Roasted Coffee, Decaffeinated Coffee, Chloronergic Acid, Obesity, Overweight, Body Fat Percent, BMI, Abdominal Fat, Antiobesity Agent, Weight Loss, Weight Decrease, Weight Gain, and Weight Control.  The exact mechanism of green coffee extract in weight loss, BMI, and body fat percentage is still unknown. The findings suggest that chlorogenic acid plays a major role in weight changes due to its various antioxidant properties and its effect on anti-inflammatory factors, which can be manifested by a reduction in weight loss, BMI, or other parameters. Some studies have also shown the effects of green coffee bean extract on the changes in liver PPAR expression.  Green coffee can affect lipid and glucose metabolism, which includes reduction of serum insulin as a result of a reduction in glucose uptake, inhibition of glucose 6 phosphatase activity, as well as suppression of lipid absorption, decrease of lipogenesis, and increase of lipolysis. These changes lead to weight loss, reduced fat percentage, and decreased BMI.

Heart disease has a direct relationship with the increase of LDL-c and decrease of HDL-c, and 8ABCG has a positive effect on these two variables by preventing atherosclerosis by interfering with the reverse transmission of cholesterol. Therefore, this study aimed to compare the effect of eight weeks aerobic training with green coffee consumption on ABCG8, leptin, and HDL gene expression in overweight women.

30 overweight young women were randomly divided into 10 groups and eight weeks of aerobic training with a frequency of three sessions per week, the intensity of 50% of the maximum heart rate, and in the last two weeks severely increased 75% of the maximum heart rate. one hour before From a practice in a one-way blind, group “Practice and green coffee” received one 400 mg capsule and group “Placebo and green coffee” received Placebo. In order to compare the variations between groups was used one-way ANOVA (P <0.05).

The results showed that the values ​​of all three variables ABCG8, leptin, and HDL-C had significant changes (p> 0.05). The LSD post hoc test in all three variables indicates a significant change between “Practice and green coffee” with Other groups.

Exercise and green coffee can affect the health of people by expression of ABCG8, an increase of HDL-C, a decrease of leptin and weight. Therefore obese people can use this type of exercise and complementary green coffee to prevent cardiovascular disease and weight loss

Chlorogenic acid, a major polyphenol in green coffee, and physical activity are considered as two possible effective factors on anxiety and depression. The aim of this study was to evaluate the effect of a six-week combined aerobic-resistance training along with green coffee consumption on anxiety and depression in overweight and obese women.
In this semi-experimental study, 30 volunteer overweight and obese women were randomly divided into three groups of combined aerobic-resistance training, green coffee and combined training with green coffee. Training was performed four sessions per week for six weeks. The amount of green coffee consumption was 250 mg per day for six weeks. The anxiety and depression levels of the participants were assessed using the Beck questionnaire.
Results showed a significant improvement in anxiety and depression levels in the three study groups (P According to the results of this study, green coffee consumption and combined training could be effective in improving anxiety and depression. Also, combined aerobic-resistance training along with green coffee consumption is more effective on improving anxiety and depression.

Introduction Polyphenols and physical activity are known as two effective factors on testosterone, Insulin-like growth factor-1(IGF-1) and cortisol hormones level. The aim of the present study was to evaluate the effect of combined training and green coffee consumption on the serum level of testosterone, IGF-1 and cortisol hormone in overweight and obese women.
Materials and Methods 30 volunteer overweight and obese women were randomly divided into three combine training, green coffee and combine training- green coffee groups. Training was conducted four times per week for six weeks. The amount of green coffee consumption was 250 mg per day for 6-weeks. The serum levels of testosterone, IGF-1 and cortisol were measured 24 h before and 48 h after the interventions.
Results The results showed no significant improvement in testosterone and cortisol serum levels in all three combine training, green coffee and the combined training-green coffee groups (p> 0.05). The IGF-1 concentrations significantly increased in the combined training group (p=0.01) and significantly decreased in the green coffee group (p=0.03) but did not change significantly in the combine training- green coffee group (p> 0.05).
Conclusion In consolation, results showed that combine training could be effective in improving IGF-1. However, green coffee and the combined training have not been effective for improving testosterone and cortisol levels. More studies are needed to confirm the findings of this study.