جستجوی مقالات مرتبط با کلیدواژه « دی ان ای » در نشریات گروه « پزشکی »

 Many scientific Researches have shown that diethylnitrosamine, which is used to induce liver carcinoma, has destructive effects on the kidney. Menthol is a monoterpene type with antioxidant, anti-inflammatory, and anti-cancer effects. In the current study, we investigated the effect of menthol on the expression of tumor-related factors and HIF-1α/VEGF signaling in the kidney cells of mice receiving diethylnitrosamine.

 In this research, 16 male mice at the age of 14 days were divided into four groups including Control, Menthol, Nitrosamine, and Nitrosamine-Menthol groups. Nitrosamine and Nitrosamine-Menthol groups received diethyl-nitrosamine intraperitoneally (25 mg/kg) at the age of 14 days. Menthol and Nitrosamine-Menthol groups also received menthol by gavage (50 mg/kg) three times a week for 6 consecutive months. At the end of this period, the expression level of SFRP1, VHL, CTNNB1, HIF-1α, and VEGF in the kidney cells was measured using real-time PCR method.

 Menthol treatment caused a significant increase in the expression level of SFRP1 (P=0.021) and VHL (P=0.013) and a significant decrease in the expression level of CTNNB1 (P=0.001), HIF-1α (P=0.000) and VEGF (P=0.000) in the kidney cells of Nitrosamine-Menthol treated group compared to the Nitrosamine group.

 The results of this study showed that menthol prevents the decrease in the expression of tumor suppressor factors and the increase in the expression of tumor stimulating factors and factors effective in angiogenesis in the kidney of mice treated with diethyl-nitrosamine, so menthol is probably useful in prevention and treatment of renal cancer.

Three oral drugs, including fingolimod, dimethyl fumarate, and teriflunomide, which are clinically approved for the therapy of relapsing–remitting multiple sclerosis (RRMS) were reviewed in this work. The present study aimed to recognize the side effects of the oral drugs in RRMS patients who were consulted in neurology clinic in west of Iran.

The study population of the present prospective observational study conducted in 2016-2017 were patients with relapsing-remitting MS referred to Imam Khomeini Hospital (RA). Three hundred patients with RRMS were randomly assigned to three treatment groups. The first group received fingolimod, the second group received dimethyl fumarate, and the third group received teriflunomide. The response to treatment assessed at 1, 3, 6, 12, and 24 months after the start of treatment. Eventually, the frequency of adverse effects characterized for each group and the collected data compared in each treatment group. The collected data were analyzed using ANOVA statistical tests.

The findings of the present study revealed that the most common clinical complications were neurological (21.8%) and gastrointestinal complications (15.6%). The most common laboratory complications were liver (12.9%) and cardiovascular complications (10.3%). Moreover, the lowest clinical complications were musculoskeletal (4.6%) and endocrine complications (3%) and lowest laboratory complications were macular edema (0.6%).

In the present study, fingolimod had the most side effects and triflunomide had the least side effects. Dimethyl fumarate was stopped due to the severity of side effects and triflunomide was continued.

Background and The objective of this study is to simulate the release of pollutant gases from the chimney of the Tabriz thermal power plant to ascertain the concentration of these pollutants in the vicinity of the power plant.  The dispersion of pollutants emitted by the Tabriz thermal power plant is modeled using AERMOD software to analyze the concentrations of sulfur dioxide and nitrogen dioxide in nearby areas and neighboring cities within a 44.85 km square. The data utilized for this modeling encompass one-year meteorological records, emission source particulars, and geographical data. This modeling calculated the distribution pattern of pollution and pollutant concentrations on the ground surface near the Tabriz thermal power plant for intervals of 1, 3, and 24 hours, as well as the annual average.  The calculated results reveal that the maximum concentrations of nitrogen dioxide in the studied area, for intervals of 1, 3, and 24 hours, and the annual average are 957, 510, 135, and 5.21 micrograms per cubic meter, respectively. Similarly, the maximum concentrations of sulfur dioxide, for the same intervals, are 3998, 2208, 584, and 22.6 micrograms per cubic meter, respectively.  The findings indicate that the maximum concentrations of sulfur dioxide and nitrogen dioxide in certain densely populated residential zones exceed the permissible limits set by environmental standards for specific criteria. Consequently, the health of residents near this power plant could be at risk.

Piezophototronic is an emerging field that has attracted the attention of many researchers in recent years. This phenomenon is based on the simultaneous effect of light radiation and mechanical stress on the electrical transport of semiconductors. In this work, the piezo phototronic phenomenon in biological DNA chains is studied. By simultaneously investigating these two external stimuli, the best conditions for flowing electric current through DNA sequences can be obtained and used to design optical and piezoelectric (piezo phototronic) detectors.

Method & Materials: 

In this work, we study the electrical current through different DNA sequences by simultaneously investigating the effect of mechanical stress and light radiation. We use the Hamiltonian model of Peyrard, Bishop and Dauxois (PBD) modified by the effects of electric field of light radiation by laser and mechanical stress caused by an external force. Then, by obtaining the evolution equations of the system and calculating the electric current through the sequence, we study the electrical transport of the system.

The results show that pseudo-ohmic regions are observed in the current-voltage characteristic diagram through the voltage variation, which can be used for designing a trivial electrical device. Then, with increasing voltage, the slope of the current-voltage characteristic diagram changes to negative. In other words, we observe negative differential resistance (NDR) phenomenon in some parameter values. The NDR region can be used for designing controllable switches. Again, with increasing voltage, we observe that such regions repeat periodically. The highest current flows through the CG-20 bp sequence at room temperature (300K) and with increasing temperature, the current through the sequence decreases.

Mechanical stress and light radiation can be influential factors on the electrical transport of a biological system based on DNA. It can be said that by adjusting the intensity and frequency of the applied force and light radiation, the current through the system can be controlled, which is useful in designing piezo phototronic devices. Piezo phototronic devices are one of the main components of detectors and biosensors that can play a significant role in diagnosing diseases and their causes.

Antibiotics are among the environmental pollutants with stable effects during consumption, they are rarely completely metabolized in the body and 30-90% of them are excreted through urine and feces and enter into the environment. The present study was conducted to evaluate the degradation of cefixime pollutant by photocatalyst Fe3O4@SiO2@TiO2@rGO + UV in the presence of persulfate (PS) from synthetic wastewater.

Fe3O4@SiO2@TiO2 (F@ST) photocatalyst was synthesized by co-precipitation method, and then fixed on reduced graphene oxide (rGO). The structural properties of magnetic photocatalyst were evaluated using FESEM, XRD, TEM, VSM techniques. The effect of variables such as solution pH, catalyst dosage, persulfate concentration and initial pollutant concentration on the performance of the FS@T/rGO/PS/UV process in the degradation of cefixime pollutant was investigated. After determining the optimal conditions, the influence of interfering ions and scavengers on the process, as well as the amount of recovery and reuse of the catalyst were investigated.

The synthesized photocatalyst had features such as excellent magnetic properties, crystalline and relatively spherical structure in nano size, high purity, photocatalytic properties in both ultraviolet and visible ranges. Under optimal conditions (pH=6.5-7, PS= 2mM and photocatalyst dosage= 0.1 g/L), after 60 min of oxidation time, cefixime antibiotic with a concentration of 50 mg/L and TOC, respectively, with efficiency > 98% and 55.7% were removed. The performance of the process was affected by the presence of organic scavengers (TBA, NaN3, KI and CH3OH) and interfering ions (Cl-, SO4-2, NO3- and CO3-2); so that the pollutant degradation efficiency decreased in the presence of organic scavengers and interfering ions. The effective reaction species were included h⁺, 1O2, OH• and SO4•⁻ in the degradation of cefixime by photocatalytic process in the presence of PS. The synthesized photocatalyst could be used for 4 consecutive steps, and in the fourth step, cefixime was degraded with an efficiency of 70.1%. The behavior of the photocatalytic degradation of cefixime antibiotic per unit time was a function of the pseudo-first-order kinetic model.

: FS@T/rGO/UV/PS photocatalytic process with features such as high efficiency in antibiotic degradation, easy and fast separation, pollutant mineralization, production of side products with simple molecular structure and good performance on the real wastewater sample could be used as a suitable method for industrial wastewater post-treatment as well as pre-treatment in order to reduce organic load and increase biodegradability.

Human health is negatively affected by increase in concentration of carbon dioxide in indoor air due to the lack of proper ventilation. The aim of this study was to remove carbon dioxide from a closed space using sodium hydroxide nanofluid and determining the effect of absorbent concentration, carbon dioxide concentration, and titanium dioxide nanoparticles.

The experiments were conducted in a closed chamber on a laboratory scale. An air suction pump was connected to the absorption reactor and the carbon dioxide measuring device was installed inside the chamber. By injecting carbon dioxide gas inside the chamber, different concentrations in the range of 500, 2000 and 5000 ppm were created. Sodium hydroxide absorbent solution at 0.1, 0.2, and 0.4% were examined. Titanium dioxide nanoparticles (0.008%) and surfactant (0.003%) were used to prepare nanofluids. The absorption fluids’ pH, electrical conductivity, and total inorganic carbon (TIC) were measured before and after carbon dioxide absorption.

By using 0.4% sodium hydroxide solution containing 0.008% titanium dioxide nanoparticles, the carbon dioxide removal efficiency at 500 and 5000 ppm were 72% and 44%, respectively, that were higher than the solution without nanoparticles (20% and 10%, respectively). At 5000 ppm carbon dioxide, increasing the concentration of absorption solution from 0.1 to 0.4% doubled the removal efficiency. The average amount of total inorganic carbon (TIC) in nanofluids increased by about 20% compared to the base fluids. The average reduction of EC in nanofluid was about 25% higher than the base fluid. The average reduction in pH value was less than one unit.

Sodium hydroxide nanofluid containing 0.008% of titanium dioxide nanoparticles is effective in removing carbon dioxide from the air.

Toluene, is usually present in gasoline, thinner, and other petroleum products and is one of the volatile organic compounds that causes air pollution and adverse health effects. The aim of this study was to determine the kinetics of toluene removal from the air by photocatalytic method using foam glass coated with titanium dioxide nanoparticles.

In this experimental study, a glass chamber was used as a closed space. A quartz tube filled by glass foam coated with titanium dioxide nanoparticles was used as air filter. The air filter was placed inside the chamber and an air suction pump was connected to it and a UV lamp was installed next to the air filter. Toluene was injected into the chamber. The contaminated air was passed through the filter and circulated in the chamber. Air samples were taken from the chamber and concentration of toluene was analyzed by Gas Chromatograph.

Brunauer-Emmett-Teller (BET) analysis showed that the average diameter of pores in glass foam was 6 nm and the specific surface area of foam glass was 36 m2/g. The SEM images confirmed coating of titanium dioxide on the surface of glass foam. Toluene removal without UV irradiation was 46%, 40%, and 37%, for 18.5, 37, and 55.5 mg/m3, respectively in 2 hour contact time, but in the presence of UV radiation the toluene removal was 100%, 95%, and 90%, respectively in contact time of 80 min. The kinetics of toluene decomposition was pseudo first order.

Glass foam can be used as a photocatalyst stabilization base to remove BTEX from the air.  This is a suitable method in removing volatile organic compounds from the air in closed spaces.

Aluminum phosphide poisoning has a high mortality rate because of the production of phosphine gas and refractory hypotension. Based on the effect of dihydroxyacetone on the treatment of hypotension and reduction of cytochrome C oxidase, the effects of dihydroxyacetone on the level of oxidative stress factors and histology of heart and liver tissue in aluminum phosphide-poisoned male rats were investigated.

In this study, 24 rats were randomly divided into 4 groups including control (corn oil), aluminum phosphide (15 mg/kg), dihydroxyacetone (50 mg/kg) and also poisoned and treated group (aluminum phosphide (15 mg/kg) + dihydroxyacetone (50 mg/kg)). After 24 hours, the animals were sacrificed and the blood, plasma, heart, and liver samples were collected then oxidative stress factors and histology of the heart and liver were investigated.

Aluminum phosphide poisoning increased lipid peroxidation in red blood cells (p=0.001) and liver tissue (p=0.023) and also increased protein carbonylation in plasma (p =0.005) and red blood cells (p=0.001). After administration of dihydroxyacetone, lipid peroxidation in red blood cells (p=0.001) and liver (p=0.001) and carbonylation of proteins in red blood cells (p=0.003) and plasma (p=0.019) decreased. No significant change was observed in total plasma antioxidant capacity, carbonylation levels of the liver and heart, and lipid peroxidation in heart tissue. In addition, treatment with dihydroxyacetone significantly improved the histological changes in liver and heart tissue.

Dihydroxyacetone not only prevents phosphine-induced deaths but also improves oxidative stress and histology of liver and heart tissue.

The emergence of new chemical industries has caused the release of a large amount of organic compounds including industrial by-products, insecticides and other chemicals in nature. Endocrine disrupting compounds are a known group of hazardous and complex pollutants that occurs in wastewater and water sources worldwide, either naturally or as a result of human activities. In this study, an attempt is made to remove diethyl phthalate from water environments by the advanced oxidation process of ozonation in the presence of activated carbon produced from the Skanbil tree.

methods and Materials:

 This experimental study was done in a reactor with a volume of 100 mL. In each experiment, diethyl phthalate solution was poured into the pilot in the desired concentration and ozone with 0.8 mg/min dose was injected into the reaction solution. Process parameters included pH (2-8), reaction times (2 to 30 min), pollutant concentration (5-25 mg/L) and catalyst dose (0.025-0.1 gram). In the end of each experiment, the sample was withdrawn from the pilot and analyzed using HPLC to determine the residual diethyl phthalate.

The results showed that under optimal conditions of pH = 6.8, ozone dose = 0.8 mg/min and contact time = 30 minutes, ozonation could only remove 60% of diethyl phthalate, and under the same conditions, catalytic ozonation with 0.075 g of carbon obtained from the skanbil tree could remove 94% of diethyl phthalate.

The results of this research showed that catalytic ozonation with carbon obtained from the wood waste of shanbil tree can be used as an advanced treatment method.

 Atopic dermatitis (AD) is a chronic inflammatory skin disease for which there is no adequate treatment. Mesenchymal stem cells have already been used to treat inflammatory diseases.  The present study investigated the effect of the administration of human mesenchymal stem cells-conditioned medium (MSC-CM) on the AD model and its relationship with central pain, the level of oxidative, and inflammatory stress factors in the skin.

 The AD model was established by topical administration of a 2% 4,2-dinitrochlorobenzene (DNCB) solution on the dorsal and ear skin of mice. Mice received topical MSC-CM and betamethasone ointment as a positive control three times a day for 2 weeks. Skin interleukin-4 (IL-4) and malondialdehyde (MDA) levels were measured by the ELISA method in all groups. Changes in nociception were assessed by the tail flick test. Histological changes in the body and ear skins were evaluated after hematoxylin-eosin (H&E) staining, and mast cells number in toluidine blue-stained sections were counted in this study.

 Topical administration of MSC-CM and betamethasone was able to reduce pain, inflammation, and changes of dermis thickness in the dorsal and ear skins, as well as the infiltration of mast cells in the skin of groups treated with DNCB. Moreover, MSC-CM, similar to betamethasone, decreased the level of IL-4 and MDA levels in the skin of DNCB receiving groups.

 The increase in IL-4 levels and lipid peroxidation play an important role in inducing AD-like lesions in the skin of the mouse in the DNCB model; in addition, the topical application of the MSC-CM is a potential therapeutic agent for AD.

Air pollution is one of the most important health risk factors in the world and one of the major causes of death and disability in the world. According to the report of the World Health Organization in 2012, about 3.7 million people in the world die due to air pollution. The purpose of the present study was to determine and investigate the health effects of air pollution in Yasuj city in 2015 using the AirQ+ model.

In the present descriptive-analytical study conducted in 2019, the hourly concentrations of particulate pollutants with a diameter of less than 2.5 microns, ozone and nitrogen dioxide in the monitoring station of Yasuj, Iran, from the environmental organization and related pressure and temperature information was obtained from the meteorological organization of the province in 2015. Validation of air quality data was done according to APHEKOM and WHO methodology, and the average specific to each pollutant was calculated and the final data file was entered into the model after processing. Finally, the city-specific annual population, the population at risk and the base incidence for each health outcome were prepared and entered into the model. At the end, the results were displayed in the form of mortality tables by the model. Collected data were analyzed using Kolmogorov Smirnov, Post hoc and Kruskal Wallis statistical tests.

The average concentration of pollutants with a diameter of less than 2.5 microns, nitrogen dioxide and ozone were 21.68±13.91, 25.41±26.88, 25.41±6.92 and 25.69±6.92 micrograms/square meter, respectively. It was micrograms per square meter. The value of SOM weight 5 was also 17.83. Regarding the long-term effects in 2015, the attributed component and the number of attributed cases of natural deaths caused by nitrogen dioxide from pollutants with a diameter of less than 2.5 microns were less, which accounted for 6.01 and 6.79% of deaths, respectively. The total number of deaths caused by pollutants with a diameter of less than 2.5 microns and nitrogen dioxide were 23 and 20, respectively. Ozone had no effect on respiratory mortality (zero cases). In the case of natural mortality, the highest and lowest attributed components were observed in pollutants with a diameter of less than 2.5 microns and ozone, respectively.

Contrary to the insignificant effect of ozone pollutant and the non-attribution of deaths to this pollutant, for other pollutants such as pollutants with a diameter of less than 2.5 microns and nitrogen dioxide, effects on the number of deaths were observed, and these effects may impose direct and indirect costs on the city.

Diallyl sulfide (DAS) is an organosulfur compound derived from garlic with antioxidative and multiple protective effects. Lipopolysaccharide (LPS) is a component of the outer membrane of Gram-negative bacteria that is commonly used to create an animal models of Acute Kidney Dysfunction (AKI). LPS can cause renal injury by induction of oxidative stress reactions. According to the role of oxidative stress in the incidence of AKI caused by sepsis, the purpose of this study was to determine the effect of DAS on acute kidney dysfunction due to LPS.

In this experimental study, 32 male C57BL / 6 mice were divided randomly into 4 groups of control, LPS, and two LPS under treatment with DAS (50, and 200 mg/kg) groups. In two DAS treatment groups, oral administration of diallyl sulfide was performed at a single dose and one hour before injection of LPS. AKI was induced by a single dose intraperitoneal injection of 10 mg/kg of LPS. Twenty-four hours after LPS injection, blood samples were collected via heart for BUN and creatinine analysis. Also, homogenization of kidney tissue was prepared to measure oxidative stress markers including malondialdehyde (MDA), nitrite, and catalase.

As compared with LPS group, DAS administered at 200 mg/kg significantly reduced MDA, but reduce in nitrite and increase in catalase activity were not significant. Also, in order to improve kidney function, it significantly reduced serum BUN and creatinine levels as compared with LPS group.

DAS can improve renal dysfunction following LPS, and its beneficial effect is through reducing oxidative stress and possible enhancement of antioxidant defence system.

Amoxicillin (AMX) is one of the commonly used commercial antibiotics due to its high resistance to bacteria and its large spectrum against a wide variety of microorganisms, which it´s existence in the wastewater from pharmaceutical industries and hospital effluents causes unpleasant odor, skin disorder, and microbial resistance among pathogen organisms, and it can lead to the death of microorganisms which are effective in wastewater treatment. Therefore, this study was conducted to investigate of removal efficacy of AMX from aqueous solutions using GO@Fe3O4@CeO2.

In this descriptive study, GO@Fe3O4@CeO2 was synthesized and then used as a photocatalyst for the removal of AMX from aqueous solution. GO@Fe3O4@CeO2 was characterized using X-Ray Diffraction (XRD), Scanning Electronic Microscopy (SEM), SEM-EDX elemental analysis, Fourier transform infrared spectroscopy (FTIR), and vibrating sample magnetometry (VSM) methods. Additionally, the influence of variables including pH (3-11), amount of photocatalyst (0.006-0.04 g), contact time (0-150 min), and temperature (25-55 °C) was assessed on the efficacy of AMX removal. 

The results indicated that removal efficiency increased up to 90 min contact time, 0.02 g of photocatalyst, and at the temperature of 25 °C. The optimum pH for AMX removal was 10.

GO@Fe3O4@CeO2 could be an effective and available photocatalyst for the removal of AMX from industrial wastewater under UV light.

Gestational diabetes mellitus (GDM) is one of the most common complications occurring during pregnancy. This disorder is associated with adverse outcomes for mothers and their infants. Air pollution is one of the environmental stimuli that may predispose pregnant women to GDM. This systematic review examined studies on the relationship between air pollution and GDM incidence.

In this systematic review, the PubMed, Web of Science, and Scopus databases, as well as Persian databases of SID, Irandoc, and Magiran, were searched for related English and Persian articles using appropriate keywords until September 11, 2021. Out of 36175 related articles in the initial search, 31 eligible studies were evaluated. The quality of the articles was assessed using the Newcastle-Ottawa scale.

The review included 29 cohort studies, a case-control study, and a cross-sectional study. The quality assessment results showed that of the 31 studies selected, 29 (93.5%) were high quality studies, and only two (6.5%) were moderate quality studies. PM2.5 pollutants followed by NO2 pollutants were the most examined in the studies.

The results showed a direct relationship between air pollutants and GDM. The systematic review of the studies revealed that inflammation, oxidative stress, β-cell dysfunction, neurological, hormonal imbalance, intestinal microbiota imbalance, and insulin resistance may be involved in the association between air pollution and GDM.

Gentamicin-induced acute renal failure (ARF) has been commonly used as a suitable animal model to research acute kidney failure in an experimental study. The sulfur dioxide (SO2), a sulfur-containing gas that considered a common air pollutant, has antioxidant effects in mammals. In this study for reducing the functional and tissue damage we use SO2 as an antioxidant agent.

Rats (n=52) were randomly assigned to four groups: 1- Sham group, 2- Gentamicin (GM) group (100 mg/kg, i.p) 3- GM + SO2 group (5 μg/kg i.p) and 4- GM + SO2 group (10 μg/kg i.p). 24-h urine samples, blood and renal tissues were collected in day eighth.

Gentamicin injection led to increase in fractional excretion of Na and K, Plasma BUN and Cr and decrease in Urine flow rate and Cr clearance compared with sham group. In addition, renal tissue MDA was increased and a Glutathione (GSH) level was decreased. SO2 injection with dose of 5 μg/kg had no statistically significant changes in BUN, fractional excretion of Na and MDA. In this group Cr and fractional excretion of K were decreased and Urine flow rate, Cr clearance and GSH were increased compared with GM group. SO2 injection with dose of 5 μg/kg caused increase in Urine flow rate, Cr clearance and renal tissue GSH and decrease in BUN, Cr, fractional excretion of K and Na and renal tissue MDA in contrast with GM group. Treatment with SO2 (5 and 10 μg/kg) significantly reduces apoptosis cell death in renal tissues compared to the GM group.

SO2 partly protected the kidneys from gentamicin induced acute kidney injury.

Tamoxifen is a group of drugs of selective estrogen receptor modulators, and is one of the drugs effective in the prevention and treatment of some cancers (such as breast cancer). In this study, the interaction of tamoxifen with DNA is investigated experimentally. Also, the electronic structure (at atomic scale) of the molecular system of tamoxifen was theoretically investigated, using atom in molecule (AIM) theory.

First, in the experimental section of this study, the interaction of Tamoxifen with DNA were investigated by UV-ViS technique and hydrodynamic method (Viscometry). In addition, the analysis of the experimental results shows the obvious effect of concentration on the mechanism of how the tamoxifen molecule binds to DNA. Then, in the theoretical part of this research, using computational biophysical chemistry methods, some properties of tamoxifen molecular system, such as electronic Density of States (DOS), boundary orbital’s energy (HOMO/LUMO), Electrostatic Potential Energy (EPS) and electronic contour maps of the electron density and its Laplacian, will be calculated.

This article is a meta-analysis with animal sample.

 Result of the UV-ViS spectroscopy technique and viscometry indicated hyperchromism and hypochromism effect. In addition, the result were depend on the concentration of the drug and affected the kind of binding of Tamoxifen to DNA. the analysis of computational studies on the drug tamoxifen suggests that the mechanism of the local charge/energy distribution in the molecular system of tamoxifen plays an important role in how this drug binds to DNA.

 Based on the experimental results of UV-ViS technique and viscometry, as well as the electronic/vibrational properties of the tamoxifen molecular system, it was defined that the Tamoxifen interacts significantly with all the binding sites of DNA.

Nitrogen oxides as one of the most dangerous environmental pollutant, have harmful effects on the health of people in the workplace. Today, the catalytic oxidation of nitrogen oxides is a highly efficient method for removing of this gases  that has been dedicated part of researches. The aim of study was to investigate the removal efficiency of  nitrogen dioxide (NO2) by nickel and nickel-platinum supported on multi-walled carbon nanotubes from air stream in the catalytic oxidation process.

In this experimental study, structural and functional specifications of the catalysts were caracterized by analysis Field Emission Scanning Electron Microscope (FE-SEM), X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR) and Temperature-Programmed Reduction (H2-TPR) after stabilization of nickel and nickel-platinum nanoparticles on carbon nanotube substrate. The removal efficiency of the synthesized catalysts were studied at the temperature of 250 °C, space velocities of 15000 – 20000 hr-1 and the NO2 concentrations  of  3000,4000,5000 ppm.

The results of FESEM  and XRD analysis showed that the diameter of carbon nanotubes ranged from 11 to 18 nm and the size of crystalline nickel and platinum nanoparticle on the catalyst bed were between 10 to 50 nm. The results of catalytic removal of NO2 showed that highest efficiency was related to the condition of  250℃temperature,  the concentration 3000 ppm and the space velocities 20000-15000 per hour.

According to the acquired results, the use of carbon nanotubes as a catalyst support is appropriate for removal of NO2 fromair stream. Bimetallic catalysts used of nickel and platinum supported on carbon nanotubes was had high efficiency and productivity in NO2 removal at various temperature, retention time, and the concentration of pollutants.